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Chengchao Ruan

Explore the profile of Chengchao Ruan including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 98
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Recent Articles
1.
Yang Y, Li X, Liu F, Ma M, Yang Y, Ruan C, et al.
JCI Insight . 2025 Mar; PMID: 40043713
This study aimed to explore the potential correlation between the metabolic intermediate L-2-hydroxyglutarate (L-2-HG) and T cell exhaustion, as well as the underlying mechanisms involved. In this study, we investigated...
2.
Zhang Q, Li H, Zhuang T, Xu L, Wu W, Pi J, et al.
Eur Heart J . 2025 Jan; PMID: 39873228
Background And Aims: Members of the CCN matricellular protein family are crucial in various biological processes. This study aimed to characterize vascular cell-specific effects of CCN5 on neointimal formation and...
3.
Zhou S, Ju S, Li X, Ruan C, Dong Z
Biochem Biophys Res Commun . 2024 Nov; 741:151042. PMID: 39586133
Abdominal aortic aneurysm (AAA) is a common cardiovascular disease in the elderly, but there are still no therapeutic targets for this disease. In this study, we collected and analyzed bulk...
4.
Bai Y, Chen L, Guo F, Zhang J, Hu J, Tao X, et al.
Signal Transduct Target Ther . 2024 Nov; 9(1):326. PMID: 39557830
EphrinB2 (erythropoietin-producing hepatoma interactor B2) is a key Eph/ephrin family member, promoting angiogenesis, vasculogenesis, and lymphangiogenesis during embryonic development. However, the role of EphrinB2 in cardiac lymphangiogenesis following myocardial infarction...
5.
Xu Z, Lu Q, Chen L, Ruan C, Bai Y, Zou Y, et al.
Methodist Debakey Cardiovasc J . 2023 Nov; 19(5):37-46. PMID: 38028969
This article highlights the importance of the structure and function of cardiac lymphatics in cardiovascular diseases and the therapeutic potential of cardiac lymphangiogenesis. Specifically, we explore the innate lymphangiogenic response...
6.
Li Y, Zhang Y, Zhang T, Ping X, Wang D, Chen Y, et al.
Adv Sci (Weinh) . 2023 Jul; 10(25):e2300436. PMID: 37407508
N6-methyladenosine (m A) modification has been implicated in the progression of obesity and metabolic diseases. However, its impact on beige fat biology is not well understood. Here, via m A-sequencing...
7.
Sun X, Ruan C, da Silva A
Front Endocrinol (Lausanne) . 2023 Jun; 14:1223983. PMID: 37388208
No abstract available.
8.
Chen X, Xu J, Bao W, Li H, Wu W, Liu J, et al.
J Am Heart Assoc . 2022 Jul; 11(15):e026378. PMID: 35904197
Background The endothelium is essential for maintaining vascular physiological homeostasis and the endothelial injury leads to the neointimal hyperplasia because of the excessive proliferation of vascular smooth muscle cells. Endothelial...
9.
Ge F, Pan Q, Qin Y, Jia M, Ruan C, Wei X, et al.
Front Cell Dev Biol . 2022 Jan; 9:786496. PMID: 35004685
Vascular aging is a potent driver of cardiovascular and cerebrovascular diseases. Vascular aging features cellular and functional changes, while its molecular mechanisms and the cell heterogeneity are poorly understood. This...
10.
Zhou W, Ji L, Liu X, Tu D, Shi N, Yangqu W, et al.
Biomed J . 2021 Dec; 45(6):870-882. PMID: 34863964
Background: Hypoxia-induced apoptosis is linked to the pathogenesis of myocardial infarction. The role of apoptosis-inducing factor mitochondria associated 1 (AIFM1) in cardiomyocyte injury remains unclear. This study was aimed at...