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Cheng-Che Lee

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Articles 31
Citations 620
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Recent Articles
1.
Lee C, Chen S, Lee T
J Cell Mol Med . 2022 May; 26(12):3396-3409. PMID: 35514058
Epidemiological studies have suggested a lower incidence of arrhythmia-induced sudden cardiac death in women than in men. 17β-oestradiol (E2) has been reported to have a post-myocardial infarction antiarrhythmic effect, although...
2.
Wang C, Lee C, Wu D, Chen S, Lee T
J Nutr Biochem . 2022 Feb; 103:108950. PMID: 35121022
The ω-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been shown to attenuate inflammation processes, whereas the molecular mechanisms remain unclear. This study was aimed at figuring...
3.
Lee T, Lee C, Harn H, Chiou T, Chuang M, Chen C, et al.
J Mol Med (Berl) . 2021 Oct; 99(12):1815-1827. PMID: 34633469
Cognitive impairment is a serious side effect of post-myocardial infarction (MI) course. We have recently demonstrated that human adipose-derived stem cells (hADSCs) ameliorated myocardial injury after MI by attenuating reactive...
4.
Lee C, Wu D, Chen S, Lin Y, Lee T
J Cell Mol Med . 2021 Jul; 25(17):8546-8557. PMID: 34328702
Oxidative damage in the brain may lead to cognitive impairments. There was considerable debate regarding the beneficial effects of physical exercise on cognitive functions because exercise protocols have varied widely...
5.
Lee C, Chen W, Chen S, Lee T
Biochem Pharmacol . 2021 Jul; 192:114674. PMID: 34252408
We have demonstrated that dapagliflozin, a sodium-glucose cotransporter (SGLT) 2 inhibitor, attenuates reactive oxygen species (ROS) production. Connexin43 playing a role in ventricular arrhythmia is sensitive to redox status. No...
6.
Lee C, Chen W, Chen S, Lee T
J Cardiovasc Pharmacol . 2021 May; 77(6):745-755. PMID: 34057159
The NLRP3 inflammasome is activated by myocardial infarction and then induces the activation of inflammatory caspase-1 activation and maturation of IL-1β, a regulator of synthesis of the nerve growth factor...
7.
Chen S, Chen L, Yeh Y, Lin C, Lin P, Huang H, et al.
Theranostics . 2021 Mar; 11(10):4672-4687. PMID: 33754020
Oxaliplatin-induced peripheral neuropathy (OIPN) is a common adverse effect that causes delayed treatment and poor prognosis among colorectal cancer (CRC) patients. However, its mechanism remains elusive, and no effective treatment...
8.
Kung B, Hu P, Huang C, Lee C, Yao C, Kuan C
IEEE J Biomed Health Inform . 2020 Nov; 25(6):1904-1914. PMID: 33136548
This paper presents a resource-saving system to extract a few important features of electrocardiogram (ECG) signals. In addition, real-time classifiers are proposed as well to classify different types of arrhythmias...
9.
Chen W, Chen S, Wu D, Lee C, Lee T
J Cell Mol Med . 2020 Jul; 24(16):9267-9279. PMID: 32639107
The ω-3 fatty acids exert as an antioxidant via the G protein-coupled receptor 120 (GPR120). Icosapent ethyl, a purified eicosapentaenoic acid, showed a marked reduction in sudden cardiac death. Connexin43...
10.
Hayashi Y, Lin H, Lee C, Tsai K
J Biomed Sci . 2020 Jan; 27(1):29. PMID: 31987051
Currently there are no therapies for treating Alzheimer's disease (AD) that can effectively halt disease progression. Existing drugs such as acetylcholinesterase inhibitors or NMDA receptor antagonists offers only symptomatic benefit....