Chen Farhy
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Explore the profile of Chen Farhy including associated specialties, affiliations and a list of published articles.
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18
Citations
769
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Recent Articles
1.
Alvarez-Kuglen M, Ninomiya K, Qin H, Rodriguez D, Fiengo L, Farhy C, et al.
Nat Aging
. 2024 Aug;
4(9):1308-1327.
PMID: 39210148
For efficient, cost-effective and personalized healthcare, biomarkers that capture aspects of functional, biological aging, thus predicting disease risk and lifespan more accurately and reliably than chronological age, are essential. We...
2.
Alvarez-Kuglen M, Rodriguez D, Qin H, Ninomiya K, Fiengo L, Farhy C, et al.
Res Sq
. 2023 Nov;
PMID: 37986947
Biomarkers of biological age that predict the risk of disease and expected lifespan better than chronological age are key to efficient and cost-effective healthcare. To advance a personalized approach to...
3.
Smith A, Ankam S, Farhy C, Fiengo L, Basa R, Gordon K, et al.
J Pharmacol Toxicol Methods
. 2022 Feb;
114:107157.
PMID: 35143957
Introduction: Despite viral suppression due to combination antiretroviral therapy (cART), HIV-associated neurocognitive disorders (HAND) continue to affect half of people with HIV, suggesting that certain antiretrovirals (ARVs) may contribute to...
4.
Farhy-Tselnicker I, Boisvert M, Liu H, Dowling C, Erikson G, Blanco-Suarez E, et al.
Elife
. 2021 Sep;
10.
PMID: 34494546
Astrocytes regulate the formation and function of neuronal synapses via multiple signals; however, what controls regional and temporal expression of these signals during development is unknown. We determined the expression...
5.
Farhy C, Hariharan S, Ylanko J, Orozco L, Zeng F, Pass I, et al.
Elife
. 2019 Oct;
8.
PMID: 31637999
High-content phenotypic screening has become the approach of choice for drug discovery due to its ability to extract drug-specific multi-layered data. In the field of epigenetics, such screening methods have...
6.
Gorshkov K, Shiryaev S, Fertel S, Lin Y, Huang C, Pinto A, et al.
Front Microbiol
. 2019 Jan;
9:3252.
PMID: 30666246
The Zika virus (ZIKV) global epidemic prompted the World Health Organization to declare it a 2016 Public Health Emergency of International Concern. The overwhelming experience over the past several years...
7.
Yang S, Xu M, Lee E, Gorshkov K, Shiryaev S, He S, et al.
Cell Discov
. 2018 Jun;
4:31.
PMID: 29872540
The re-emergence of Zika virus (ZIKV) and Ebola virus (EBOV) poses serious and continued threats to the global public health. Effective therapeutics for these maladies is an unmet need. Here,...
8.
Shiryaev S, Mesci P, Pinto A, Fernandes I, Sheets N, Shresta S, et al.
Sci Rep
. 2017 Nov;
7(1):15771.
PMID: 29150641
One of the major challenges of the current Zika virus (ZIKV) epidemic is to prevent congenital foetal abnormalities, including microcephaly, following ZIKV infection of pregnant women. Given the urgent need...
9.
Shiryaev S, Farhy C, Pinto A, Huang C, Simonetti N, Elong Ngono A, et al.
Antiviral Res
. 2017 May;
143:218-229.
PMID: 28461069
The recent re-emergence of Zika virus (ZIKV), a member of the Flaviviridae family, has become a global emergency. Currently, there are no effective methods of preventing or treating ZIKV infection,...
10.
Naftelberg S, Abramovitch Z, Gluska S, Yannai S, Joshi Y, Donyo M, et al.
PLoS Genet
. 2016 Dec;
12(12):e1006486.
PMID: 27997532
Familial Dysautonomia (FD) is a neurodegenerative disease in which aberrant tissue-specific splicing of IKBKAP exon 20 leads to reduction of IKAP protein levels in neuronal tissues. Here we generated a...