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Che Serguera

Explore the profile of Che Serguera including associated specialties, affiliations and a list of published articles. Areas
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Articles 22
Citations 399
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Recent Articles
1.
Stimmer L, Confais J, Jong A, Veth J, Fovet C, Horellou P, et al.
Lab Invest . 2021 Aug; 101(11):1513-1522. PMID: 34376778
Experimental autoimmune encephalitis (EAE) is a well-recognized model for the study of human acquired demyelinating diseases (ADD), a group of inflammatory disorders of the central nervous system (CNS) characterized by...
2.
Horellou P, Chalus A, Giorgi L, Leroy C, Chretien P, Hacein-Bey-Abina S, et al.
Front Immunol . 2021 Jul; 12:679770. PMID: 34220827
Background: Myelin oligodendrocytes glycoprotein (MOG) antibody-associated disease (MOGAD) represent 25% of pediatric acquired demyelinating syndrome (ADS); 40% of them may relapse, mimicking multiple sclerosis (MS), a recurrent and neurodegenerative ADS,...
3.
Serguera C, Stimmer L, Fovet C, Horellou P, Contreras V, Tchitchek N, et al.
J Neuroinflammation . 2019 Dec; 16(1):244. PMID: 31785610
Background: Autoantibodies against myelin oligodendrocyte glycoprotein (anti-MOG-Abs) occur in a majority of children with acquired demyelinating syndromes (ADS) and physiopathology is still under investigation. As cynomolgus macaques immunized with rhMOG,...
4.
Fovet C, Stimmer L, Contreras V, Horellou P, Hubert A, Seddiki N, et al.
EBioMedicine . 2019 Sep; 47:492-505. PMID: 31492559
Background: Autoimmune demyelinating diseases (ADD) are a major cause of neurological disability due to autoreactive cellular and humoral immune responses against brain antigens. A cure for chronic ADD could be...
5.
Cobo-Calvo A, Ayrignac X, Kerschen P, Horellou P, Cotton F, Labauge P, et al.
Neurol Neuroimmunol Neuroinflamm . 2019 Feb; 6(2):e543. PMID: 30800725
Objective: To describe clinical and radiologic features of cranial nerve (CN) involvement in patients with myelin oligodendrocyte glycoprotein antibodies (MOG-IgG) and to assess the potential underlying mechanism of CN involvement...
6.
Bitoun S, Roques P, Larcher T, Nocturne G, Serguera C, Chretien P, et al.
Front Immunol . 2018 Jan; 8:1816. PMID: 29326703
Objectives: Anti-citrullinated peptides antibodies (ACPAs) have high specificity for the diagnosis of rheumatoid arthritis (RA), but their role in the pathophysiology is not fully established. The main genetic risk factor...
7.
Stimmer L, Fovet C, Serguera C
Vet Pathol . 2017 Jun; 55(1):27-41. PMID: 28583039
Human idiopathic inflammatory demyelinating diseases (IIDD) are a heterogeneous group of autoimmune inflammatory and demyelinating disorders of the central nervous system (CNS). These include multiple sclerosis (MS), the most common...
8.
Gutierrez D, Valdes L, Serguera C, Llano M
J Gen Virol . 2016 Mar; 97(7):1686-1692. PMID: 27028089
PARP-1 silences retrotransposons in Drosophila, through heterochromatin maintenance, and integrated retroviruses in chicken. Here, we determined the role of viral DNA integration and cellular heterochromatin in PARP-1-mediated retroviral silencing using...
9.
Horellou P, Wang M, Keo V, Chretien P, Serguera C, Waters P, et al.
J Neuroimmunol . 2015 Dec; 289:1-7. PMID: 26616865
Acquired demyelinating syndromes (ADS) in children evolve either as a monophasic disease diagnosed as acute demyelinating encephalomyelitis (ADEM), transverse myelitis (TM) or optic neuritis (ON), or a multiphasic one with...
10.
Saeed M, Dufour N, Bartholmae C, Sieranska U, Knopf M, Thierry E, et al.
Mol Ther Nucleic Acids . 2014 Dec; 3:e213. PMID: 25462529
HIV-1 derived vectors are among the most efficient for gene transduction in mammalian tissues. As the parent virus, they carry out vector genome insertion into the host cell chromatin. Consequently,...