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Chathura Paththamperuma

Explore the profile of Chathura Paththamperuma including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Stewart M, Paththamperuma C, McCann C, Cottingim K, Zhang H, DelVecchio R, et al.
bioRxiv . 2025 Mar; PMID: 40027613
Protein quality control is crucial for cellular homeostasis, involving the heat shock response, the ubiquitin-proteasome system, and the autophagy-lysosome pathway. Central to these systems are the chaperone homologs heat shock...
2.
Paththamperuma C, Page R
Anal Biochem . 2022 Oct; 659:114954. PMID: 36265691
Tobacco etch virus (TEV) protease is a widely used protease for fusion tag cleavage. Despite its widespread usage, an assay to quickly and easily quantify its activity in laboratory settings...
3.
Zhang H, Yang K, Cheng Z, Thomas C, Steinbrunner A, Pryor C, et al.
Bioorg Med Chem . 2021 May; 40:116183. PMID: 33965839
In an effort to probe the biophysical mechanisms of inhibition for ten previously-reported inhibitors of metallo-β-lactamases (MBL) with MBL IMP-1, equilibrium dialysis, metal analyses coupled with atomic absorption spectroscopy (AAS),...