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Charlotte H Dean

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Articles 39
Citations 728
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Recent Articles
11.
Kim S, Mongey R, Wang P, Rothery S, Gaboriau D, Hind M, et al.
Biomaterials . 2020 Nov; 267:120480. PMID: 33157373
Research into mechanisms underlying lung injury and subsequent repair responses is currently of paramount importance. There is a paucity of models that bridge the gap between in vitro and in...
12.
Taylor B, Rice A, Nicholson A, Hind M, Dean C
Thorax . 2020 Aug; 75(11):1001-1003. PMID: 32732323
Congenital pulmonary airway malformations (CPAMs) are rare lung abnormalities that result in cyst formation and are associated with respiratory distress in infants and malignant potential in adults. The pathogenesis of...
13.
Portas L, Pereira M, Shaheen S, Wyss A, London S, Burney P, et al.
Am J Respir Crit Care Med . 2020 May; 202(6):853-865. PMID: 32392078
Poor lung health in adult life may occur partly through suboptimal growth and development, as suggested by epidemiological evidence pointing to early life risk factors. To systematically investigate the effects...
14.
Rao-Bhatia A, Zhu M, Yin W, Coquenlorge S, Zhang X, Woo J, et al.
Dev Cell . 2020 Mar; 52(5):647-658.e6. PMID: 32155439
During development, intestinal epithelia undergo dramatic morphogenesis mediated by mesenchymal signaling to form villi, which are required for efficient nutrient absorption and host defense. Although both smooth-muscle-induced physical forces and...
15.
Akram K, Yates L, Mongey R, Rothery S, Gaboriau D, Sanderson J, et al.
Nat Commun . 2019 Mar; 10(1):1178. PMID: 30862802
Damage to alveoli, the gas-exchanging region of the lungs, is a component of many chronic and acute lung diseases. In addition, insufficient generation of alveoli results in bronchopulmonary dysplasia, a...
16.
Cheong S, Dean C
Am J Respir Cell Mol Biol . 2018 Nov; 60(4):377-378. PMID: 30423257
No abstract available.
17.
Papakrivopoulou E, Vasilopoulou E, Lindenmeyer M, Pacheco S, Brzoska H, Price K, et al.
J Pathol . 2018 Aug; 246(4):485-496. PMID: 30125361
Planar cell polarity (PCP) pathways control the orientation and alignment of epithelial cells within tissues. Van Gogh-like 2 (Vangl2) is a key PCP protein that is required for the normal...
18.
Henderson D, Long D, Dean C
Curr Opin Cell Biol . 2018 Jul; 55:96-103. PMID: 30015152
The planar cell polarity (PCP) pathway controls a variety of morphological events across many species. During embryonic development, the PCP pathway regulates coordinated behaviour of groups of cells to direct...
19.
Dean C, Snelgrove R
Am J Respir Crit Care Med . 2018 Jun; 198(11):1355-1356. PMID: 29877729
No abstract available.
20.
Zhang Y, Poobalasingam T, Yates L, Walker S, Taylor M, Chessum L, et al.
Dis Model Mech . 2018 Jan; 11(1). PMID: 29361513
We previously identified dipeptidylpeptidase 10 () on chromosome 2 as a human asthma susceptibility gene, through positional cloning. Initial association results were confirmed in many subsequent association studies but the...