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Charlie Mantel

Explore the profile of Charlie Mantel including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 1043
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Park S, Lee S, Prasain N, Bae D, Kang H, Ha T, et al.
Stem Cells Dev . 2017 Mar; 26(10):734-742. PMID: 28346802
Acquisition of proper metabolomic fate is required to convert somatic cells toward fully reprogrammed pluripotent stem cells. The majority of induced pluripotent stem cells (iPSCs) are partially reprogrammed and have...
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Lee M, Mantel C, Lee S, Moon S, Broxmeyer H
Stem Cell Reports . 2016 Jun; 7(1):1-10. PMID: 27346679
Metabolism is remodeled when somatic cells are reprogrammed into induced pluripotent stem cells (iPSCs), but the majority of iPSCs are not fully reprogrammed. In a shift essential for reprogramming, iPSCs...
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Broxmeyer H, OLeary H, Huang X, Mantel C
Curr Opin Hematol . 2015 Jun; 22(4):273-8. PMID: 26049746
Purpose Of Review: Hematopoietic stem (HSCs) and progenitor (HPCs) cells reside in a hypoxic (lowered oxygen tension) environment, in vivo. We review literature on growth of HSCs and HPCs under...
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Lee J, Hong K, Mantel C, Broxmeyer H, Lee M, Kim K
Stem Cells Dev . 2013 Jun; 22(20):2706-13. PMID: 23746070
In this study, we isolated and characterized spontaneously differentiated human embryonic stem cells (SD-hESCs) found in hESC colonies in comparison to the morphologically premature ESCs in the colonies to investigate...
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Lee M, Prasain N, Chae H, Kim Y, Mantel C, Yoder M, et al.
Stem Cells . 2012 Dec; 31(4):666-81. PMID: 23255147
While most somatic cells undergoing induced pluripotent stem (iPS) cell reprogramming with Yamanaka factors accumulate at stable partially reprogrammed stages, the molecular mechanisms required to achieve full reprogramming are unknown....
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Broxmeyer H, Hoggatt J, OLeary H, Mantel C, Chitteti B, Cooper S, et al.
Nat Med . 2012 Nov; 18(12):1786-96. PMID: 23160239
Enhancement of hematopoietic recovery after radiation, chemotherapy, or hematopoietic stem cell (HSC) transplantation is clinically relevant. Dipeptidylpeptidase (DPP4) cleaves a wide variety of substrates, including the chemokine stromal cell-derived factor-1...
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Broxmeyer H, Mantel C
Nat Med . 2012 Sep; 18(9):1334-6. PMID: 22961159
No abstract available.
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Mantel C, Messina-Graham S, Moh A, Cooper S, Hangoc G, Fu X, et al.
Blood . 2012 Jun; 120(13):2589-99. PMID: 22665934
Nuclear transcription factor Stat3 is important for proper regulation of hematopoietic stem cell (HSC) and hematopoietic progenitor cell (HPC) proliferation, survival, and cytokine signaling responses. A new, noncanonical role for...
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Broxmeyer H, Christopherson K, Hangoc G, Cooper S, Mantel C, Renukaradhya G, et al.
Blood . 2012 Apr; 119(24):5731-41. PMID: 22535665
In the present study, surface CD1d, which is involved in immune cell interactions, was assessed for effects on hematopoiesis. Mouse BM hematopoietic stem cells (HSCs) and hematopoietic progenitor cells (HPCs)...