Charles W Heilig
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Explore the profile of Charles W Heilig including associated specialties, affiliations and a list of published articles.
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20
Citations
599
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Recent Articles
1.
Galloway M, Mellin L, Retamales V, Heilig C
Neuromuscul Disord
. 2025 Jan;
47:105271.
PMID: 39824030
Sengers Syndrome (SS) is a rare autosomal recessive mitochondrial disorder caused by mutations in the acylglycerol kinase (AGK) gene on chromosome 7, also known as cardiomyopathic mitochondrial DNA depletion syndrome...
2.
Hasan I, Rashid T, Suliman S, Amer H, Chirila R, Mai M, et al.
Rom J Intern Med
. 2020 Nov;
59(1):10-42.
PMID: 33155999
COVID-19 presents a special challenge to the kidney transplant population. A systematic review of articles that examined COVID-19 in kidney transplant recipients was performed. Patients' demographics, clinical, laboratory and radiological...
3.
Suliman S, Carlson J, Smotherman C, Gautam S, Heilig C, Munroe C, et al.
Clin Nephrol
. 2019 Sep;
92(5):221-225.
PMID: 31496515
Background: Multiple studies have revealed disparity in renal healthcare access and outcomes in racial/ethnic minorities with the socioeconomic status explaining the majority but not all of the disparity. We wanted...
4.
Kunjal R, Adam-Eldien R, Makary R, Jo-Hoy F, Heilig C
Case Rep Nephrol Dial
. 2016 Oct;
6(3):101-105.
PMID: 27781205
We report the case of a 22-year-old African American female who presented to another facility for routine follow-up in the 34th week of pregnancy with lower extremity swelling and nephrotic-range...
5.
Heilig C, Deb D, Abdul A, Riaz H, James L, Salameh J, et al.
Am J Nephrol
. 2013 Jul;
38(1):39-49.
PMID: 23817135
Diabetic glomerulosclerosis is characterized by accumulation of extracellular matrix proteins, mesangial expansion, and tubulointerstitial fibrosis. Hyperglycemia accelerates development of the disease, a direct result of increased intracellular glucose availability. The...
6.
Marin-Valencia I, Good L, Ma Q, Duarte J, Bottiglieri T, Sinton C, et al.
Neurobiol Dis
. 2012 Jun;
48(1):92-101.
PMID: 22683290
Brain glucose supplies most of the carbon required for acetyl-coenzyme A (acetyl-CoA) generation (an important step for myelin synthesis) and for neurotransmitter production via further metabolism of acetyl-CoA in the...
7.
Buller C, Heilig C, Brosius 3rd F
Am J Physiol Renal Physiol
. 2011 May;
301(3):F588-96.
PMID: 21613414
Enhanced GLUT1 expression in mesangial cells plays an important role in the development of diabetic nephropathy by stimulating signaling through several pathways resulting in increased glomerular matrix accumulation. Similarly, enhanced...
8.
Hsu C, Kao W, Steffes M, Gambir T, Brancati F, Heilig C, et al.
BMC Med Genet
. 2011 Jan;
12:16.
PMID: 21247498
Background: Evidence suggests glucose transporter-1 (GLUT1) genetic variation affects diabetic nephropathy and albuminuria. Our aim was to evaluate associations with albuminuria of six GLUT1 single nucleotide polymorphisms(SNPs), particularly XbaI and...
9.
Wang Y, Heilig K, Saunders T, Minto A, Deb D, Chang A, et al.
Am J Physiol Renal Physiol
. 2010 Apr;
299(1):F99-F111.
PMID: 20375117
Previous work identified an important role for hyperglycemia in diabetic nephropathy (The Diabetes Control and Complications Trial Research Group. N Engl J Med 329: 977-986, 1993; UK Prospective Diabetes Study...
10.
Zhang H, Schin M, Saha J, Burke K, Holzman L, Filipiak W, et al.
Am J Physiol Renal Physiol
. 2010 Apr;
299(1):F91-8.
PMID: 20375116
Increased expression of the facilitative glucose transporter, GLUT1, leads to glomerulopathy that resembles diabetic nephropathy, whereas prevention of enhanced GLUT1 expression retards nephropathy. While many of the GLUT1-mediated effects are...