Charles W Emala Sr
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Explore the profile of Charles W Emala Sr including associated specialties, affiliations and a list of published articles.
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25
Citations
524
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Recent Articles
1.
Emala Sr C, Tawfik V, Lane-Fall M, Toledo P, Wong C, Vavilala M, et al.
Anesth Analg
. 2023 Sep;
137(4):728-742.
PMID: 37712462
The limited number and diversity of resident physicians pursuing careers as physician-scientists in medicine has been a concern for many decades. The Anesthesia Research Council aimed to address the status...
2.
Sasaki H, Zhang Y, Emala Sr C, Mizuta K
Am J Physiol Lung Cell Mol Physiol
. 2021 Oct;
321(6):L991-L1005.
PMID: 34612067
Nocturnal asthma is characterized by heightened bronchial reactivity at night, and plasma melatonin concentrations are higher in patients with nocturnal asthma symptoms. Numerous physiological effects of melatonin are mediated via...
3.
Mizuta K, Sasaki H, Zhang Y, Matoba A, Emala Sr C
Am J Physiol Lung Cell Mol Physiol
. 2020 Mar;
318(6):L1248-L1260.
PMID: 32209026
Emerging evidence suggests that gut microbiota-derived short-chain fatty acids (SCFAs; acetate, propionate, and butyrate) are important modulators of the inflammatory state in diseases such as asthma. However, the functional expression...
4.
Urso A, DOvidio F, Xu D, Emala Sr C, Bunnett N, Perez-Zoghbi J
Am J Physiol Lung Cell Mol Physiol
. 2019 Dec;
318(2):L264-L275.
PMID: 31800261
Duodenogastroesophageal reflux (DGER) is associated with chronic lung disease. Bile acids (BAs) are established markers of DGER aspiration and are important risk factors for reduced post-transplant lung allograft survival by...
5.
Danielsson J, Kuforiji A, Yocum G, Zhang Y, Xu D, Gallos G, et al.
Am J Physiol Lung Cell Mol Physiol
. 2019 Nov;
318(2):L287-L295.
PMID: 31747299
TMEM16A (anoctamin 1) is an important calcium-activated chloride channel in airway smooth muscle (ASM). We have previously shown that TMEM16A antagonists such as benzbromarone relax ASM and have proposed TMEM16A...
6.
Mizuta K, Matoba A, Shibata S, Masaki E, Emala Sr C
Jpn Dent Sci Rev
. 2019 Sep;
55(1):103-107.
PMID: 31516639
Obesity is a major risk factor for the development of asthma, and worsens the key features of asthma including airway hyperresponsiveness, inflammation, and airway remodeling. Although pro- and anti-inflammatory adipocytokines...
7.
Yocum G, Perez-Zoghbi J, Danielsson J, Kuforiji A, Zhang Y, Li G, et al.
Am J Physiol Lung Cell Mol Physiol
. 2018 Nov;
316(2):L385-L390.
PMID: 30489155
Airway smooth muscle (ASM) cells express GABA A receptors (GABARs), and previous reports have demonstrated that GABAR activators relax ASM. However, given the activity of GABARs in central nervous system...
8.
Mikami M, Perez-Zoghbi J, Zhang Y, Emala Sr C
Am J Physiol Lung Cell Mol Physiol
. 2018 Nov;
316(1):L105-L113.
PMID: 30407863
We have previously reported that mice genetically deficient in the actin binding protein gelsolin exhibit impaired airway smooth muscle (ASM) relaxation. Primary cultured ASM cells from these mice demonstrate enhanced...
9.
Emala Sr C
Am J Respir Cell Mol Biol
. 2018 Nov;
60(5):492-493.
PMID: 30399322
No abstract available.
10.
Matoba A, Matsuyama N, Shibata S, Masaki E, Emala Sr C, Mizuta K
Am J Physiol Lung Cell Mol Physiol
. 2017 Nov;
314(3):L333-L348.
PMID: 29097424
Obesity is a risk factor for asthma and influences airway hyperresponsiveness, which is in part modulated by airway smooth muscle proliferative remodeling. Plasma free fatty acids (FFAs) levels are elevated...