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Charles L McCormick

Explore the profile of Charles L McCormick including associated specialties, affiliations and a list of published articles. Areas
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Articles 27
Citations 420
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Recent Articles
1.
Fortenberry A, Jankoski P, Stacy E, McCormick C, Smith A, Clemons T
Macromol Rapid Commun . 2022 Jul; 43(24):e2200414. PMID: 35822936
Reversible addition-fragmentation chain transfer (RAFT) polymerization has proven itself as a powerful polymerization technique affording facile control of molecular weight, molecular weight distribution, architecture, and chain end groups - while...
2.
McAfee T, Ferron T, Cordova I, Pickett P, McCormick C, Wang C, et al.
Nat Commun . 2021 May; 12(1):3123. PMID: 34035289
Self-assembled molecular nanostructures embody an enormous potential for new technologies, therapeutics, and understanding of molecular biofunctions. Their structure and function are dependent on local environments, necessitating in-situ/operando investigations for the...
3.
Parsons K, Mondal M, McCormick C, Flynt A
Biomacromolecules . 2018 Feb; 19(4):1111-1117. PMID: 29446934
RNAi-based technologies are ideal for pest control as they can provide species specificity and spare nontarget organisms. However, in some pests biological barriers prevent use of RNAi, and therefore broad...
4.
Das P, Dean D, Fogel A, Liu F, Abel B, McCormick C, et al.
Biomacromolecules . 2017 Sep; 18(10):3359-3366. PMID: 28893064
GM1 ganglioside is known to promote amyloid-β (Aβ) peptide aggregation in Alzheimer's disease. The roles of the individual saccharides and their distribution in this process are not understood. Acrylamide-based glycomonomers...
5.
Parsons K, Holley A, Munn G, Flynt A, McCormick C
Polym Chem . 2017 Feb; 7(39):6044-6054. PMID: 28239425
Block ionomer complex (BIC)-siRNA interactions and effectiveness in cell transfection are reported. Aqueous RAFT polymerization was used to prepare a series of hydrophilic--cationic copolymers in which the cationic block statistically...
6.
Exley S, Paslay L, Sahukhal G, Abel B, Brown T, McCormick C, et al.
Biomacromolecules . 2015 Nov; 16(12):3845-52. PMID: 26558609
Naturally occurring antimicrobial peptides (AMPs) display the ability to eliminate a wide variety of bacteria, without toxicity to the host eukaryotic cells. Synthetic polymers containing moieties mimicking lysine and arginine...
7.
Holley A, Ray J, Wan W, Savin D, McCormick C
Biomacromolecules . 2013 Sep; 14(10):3793-9. PMID: 24044682
A facile synthetic pathway for preparing block copolymers with pH-responsive L-glutamic acid segments for membrane disruption is reported. Aqueous reversible addition-fragmentation chain transfer (aRAFT) polymerization was first used to prepare...
8.
Paslay L, Abel B, Brown T, Koul V, Choudhary V, McCormick C, et al.
Biomacromolecules . 2012 Jun; 13(8):2472-82. PMID: 22738241
Antimicrobial peptides (AMPs) show great potential as alternative therapeutic agents to conventional antibiotics as they can selectively bind and eliminate pathogenic bacteria without harming eukaryotic cells. It is of interest...
9.
Treat N, Smith D, Teng C, Flores J, Abel B, York A, et al.
ACS Macro Lett . 2012 May; 1(1):100-104. PMID: 22639734
We report the synthesis and controlled radical homo- and block copolymerization of 3-guanidinopropyl methacrylamide (GPMA) utilizing aqueous reversible addition-fragmentation chain transfer (aRAFT) polymerization. The resulting homopolymer and block copolymer with...
10.
Kirkland-York S, Zhang Y, Smith A, York A, Huang F, McCormick C
Biomacromolecules . 2010 Mar; 11(4):1052-9. PMID: 20337403
The facile synthesis of polymer-stabilized Au nanoparticles (AuNPs) capable of forming neutral, sterically stable complexes with small interfering RNA (siRNA) is reported. The amine-containing cationic block of poly(N-2-hydroxypropyl methacrylamide(70)-block-N-[3-(dimethylamino)propyl] methacrylamide(24))...