Charles L Liotta
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Explore the profile of Charles L Liotta including associated specialties, affiliations and a list of published articles.
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43
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826
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Recent Articles
1.
Chang Y, Blanton S, Andraos R, Nguyen V, Liotta C, Schork F, et al.
ACS Sustain Chem Eng
. 2024 Jan;
12(1):178-191.
PMID: 38213546
Synthetic polyolefinic plastics comprise one of the largest shares of global plastic waste, which is being targeted for chemical recycling by depolymerization to monomers and small molecules. One promising method...
2.
Yi R, Mojica M, Fahrenbach A, James Cleaves 2nd H, Krishnamurthy R, Liotta C
JACS Au
. 2023 Sep;
3(9):2522-2535.
PMID: 37772180
Carbohydrate biosynthesis is fundamental to modern terrestrial biochemistry, but how this collection of metabolic pathways originated remains an open question. Prebiotic sugar synthesis has focused primarily on the formose reaction...
3.
Yi R, Kern R, Pollet P, Lin H, Krishnamurthy R, Liotta C
Chemistry
. 2022 Nov;
29(8):e202202816.
PMID: 36367459
The prebiotic generation of sugars in the context of origins of life studies is of considerable interest. Among the important intramolecular processes of sugars are carbonyl migrations and accompanying epimerizations....
4.
C M, Frenkel-Pinter M, Smith K, Rivera-Santana V, Sargon A, Jacobson K, et al.
JACS Au
. 2022 Jul;
2(6):1395-1404.
PMID: 35783166
The high kinetic barrier to amide bond formation has historically placed narrow constraints on its utility in reversible chemistry applications. Slow kinetics has limited the use of amides for the...
5.
McKenna K, Clowers B, Krishnamurthy R, Liotta C, Fernandez F
J Am Soc Mass Spectrom
. 2021 Aug;
32(9):2472-2480.
PMID: 34351139
An increased focus on characterizing the structural heterogeneity of carbohydrates has been driven by their many significant roles in extant life and potential roles in chemical evolution and the origin...
6.
McKenna K, Li L, Krishnamurthy R, Liotta C, Fernandez F
Analyst
. 2020 Oct;
145(24):8008-8015.
PMID: 33052364
Carbohydrates are the most abundant class of biomolecules on Earth with a diverse array of biological functions. It is hypothesized that they likely had an important role in the development...
7.
Sun Y, Frenkel-Pinter M, Liotta C, Grover M
Phys Chem Chem Phys
. 2019 Dec;
22(1):107-113.
PMID: 31807746
The non-enzymatic cleavage rates of amide bonds located in peptides in aqueous solution is pH-dependent and involves two distinct mechanisms: direct hydrolysis (herein termed "scission") and intramolecular aminolysis by the...
8.
Li Z, Li L, McKenna K, Schmidt M, Pollet P, Gelbaum L, et al.
Orig Life Evol Biosph
. 2019 Dec;
49(4):225-240.
PMID: 31792744
The prebiotic origin of polysaccharides, the largest class of biopolymers by mass in extant biology, has seldom been investigated experimentally. Herein, we report on the acid-catalyzed condensation of aqueous solutions...
9.
McKenna K, Li L, Baker A, Ujma J, Krishnamurthy R, Liotta C, et al.
Analyst
. 2019 Nov;
144(24):7220-7226.
PMID: 31670330
Oligosaccharides serve many roles in extant life and may have had a significant role in prebiotic chemistry on the early Earth. In both these contexts, the structural and isomeric diversity...
10.
Ward G, Liotta C, Krishnamurthy R, France S
J Org Chem
. 2018 Sep;
83(23):14219-14233.
PMID: 30223647
The diester derivative of dihydroxyfumaric acid (DHF) has been used exclusively as an electrophile in organic synthesis. However, the synthetic utility of DHF's nucleophilic reactivity, contained in the ene-diol moiety,...