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Charles K Perry

Explore the profile of Charles K Perry including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 56
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Recent Articles
1.
Kwon J, Hajian B, Bian Y, Young L, Amor A, Fuller J, et al.
Nature . 2022 Jul; 609(7926):408-415. PMID: 35831509
Receptor tyrosine kinase (RTK)-RAS signalling through the downstream mitogen-activated protein kinase (MAPK) cascade regulates cell proliferation and survival. The SHOC2-MRAS-PP1C holophosphatase complex functions as a key regulator of RTK-RAS signalling...
2.
Perry C, Casey A, Felsing D, Vemula R, Zaka M, Herrington N, et al.
Bioorg Med Chem . 2019 Dec; 28(3):115262. PMID: 31882369
The serotonin 5-HT G protein-coupled receptor (GPCR) is a proposed pharmacotherapeutic target for a variety of central and peripheral indications, albeit, there are no approved drugs selective for binding 5-HT....
3.
Presley C, Perry C, Childress E, Mulder M, Luscombe V, Rodriguez A, et al.
ACS Omega . 2019 Aug; 4(7):12782-12789. PMID: 31460402
Allosteric ligands within a given chemotype can have the propensity to display a wide range of pharmacology, as well as unexpected changes in GPCR subtype selectivity, typically mediated by single-atom...
4.
Canal C, Felsing D, Liu Y, Zhu W, Wood J, Perry C, et al.
ACS Chem Neurosci . 2015 Jul; 6(8):1486. PMID: 26225542
No abstract available.
5.
Canal C, Felsing D, Liu Y, Zhu W, Wood J, Perry C, et al.
ACS Chem Neurosci . 2015 May; 6(7):1259-70. PMID: 26011730
Stereotypy (e.g., repetitive hand waving) is a key phenotype of autism spectrum disorder, Fragile X and Rett syndromes, and other neuropsychiatric disorders, and its severity correlates with cognitive and attention...