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Charles H McDonnell 3rd

Explore the profile of Charles H McDonnell 3rd including associated specialties, affiliations and a list of published articles. Areas
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Citations 271
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Recent Articles
1.
Nadauld L, McDonnell 3rd C, Dilaveri C, Klein E, Reid R, Marinac C, et al.
Lancet Oncol . 2025 Jan; 26(2):165-174. PMID: 39818231
Background: PATHFINDER was a prospective cohort study of multicancer early detection (MCED) testing in an outpatient ambulatory population. The aim of this study is to report the patient-reported outcomes (PROs)...
2.
Schrag D, Beer T, McDonnell 3rd C, Nadauld L, Dilaveri C, Reid R, et al.
Lancet . 2023 Oct; 402(10409):1251-1260. PMID: 37805216
Background: Multicancer early detection (MCED) blood tests can detect a cancer signal from circulating cell-free DNA (cfDNA). PATHFINDER was a prospective cohort study investigating the feasibility of MCED testing for...
3.
Nadauld L, McDonnell 3rd C, Beer T, Liu M, Klein E, Hudnut A, et al.
Cancers (Basel) . 2021 Jul; 13(14). PMID: 34298717
To examine the extent of the evaluation required to achieve diagnostic resolution and the test performance characteristics of a targeted methylation cell-free DNA (cfDNA)-based multi-cancer early detection (MCED) test, ~6200...
4.
Ding L, Su Y, Fassl A, Hinohara K, Qiu X, Harper N, et al.
Nat Commun . 2019 Sep; 10(1):4182. PMID: 31519911
Myoepithelial cells play key roles in normal mammary gland development and in limiting pre-invasive to invasive breast tumor progression, yet their differentiation and perturbation in ductal carcinoma in situ (DCIS)...
5.
Gil Del Alcazar C, Huh S, Ekram M, Trinh A, Liu L, Beca F, et al.
Cancer Discov . 2017 Jun; 7(10):1098-1115. PMID: 28652380
To investigate immune escape during breast tumor progression, we analyzed the composition of leukocytes in normal breast tissues, ductal carcinoma (DCIS), and invasive ductal carcinomas (IDC). We found significant tissue...