Charles Dumontet
Overview
Explore the profile of Charles Dumontet including associated specialties, affiliations and a list of published articles.
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Articles
273
Citations
7872
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Recent Articles
1.
Sesques P, Karlin L, Massy E, Maarek A, Aussedat G, Lazareth A, et al.
Front Oncol
. 2024 Nov;
14:1436587.
PMID: 39544298
Background: In spite of spectacular advances in the treatment of multiple myeloma, a majority of patients will die from this disease or related complications. While a great amount of focus...
2.
Ciniero G, Pedro T, Dumontet C, Elmenoufy A, West F, Weinfeld M, et al.
Fundam Clin Pharmacol
. 2024 Nov;
39(1):e13043.
PMID: 39520092
Background: DNA repair plays a major role in maintaining genomic stability, thus limiting the transformation of normal cells into cancer cells. However, in cancer patients treated with DNA-targeting drugs, DNA...
3.
Eckmann J, Fauti T, Biehl M, Zabaleta A, Blanco L, Lelios I, et al.
Blood
. 2024 Oct;
145(2):202-219.
PMID: 39476124
Despite several approved therapies, multiple myeloma (MM) remains an incurable disease with high unmet medical need. "Off-the-shelf" T-cell bispecific antibodies (TCBs) targeting B-cell maturation antigen (BCMA) and G protein-coupled receptor...
4.
Pemov A, Kim J, Luo W, Liu J, Graham C, Jones K, et al.
Blood Neoplasia
. 2024 Jul;
1(2).
PMID: 39036705
Waldenström macroglobulinemia (WM) is a rare hematological malignancy. Risk for WM is elevated 20-fold among first-degree relatives of patients with WM. However, the list of variants and genes that cause...
5.
Gouez M, Rebillard A, Thomas A, Beaumel S, Matera E, Gouraud E, et al.
Front Immunol
. 2024 Mar;
15:1368550.
PMID: 38426110
Acute exercise induces transient modifications in the tumor microenvironment and has been linked to reduced tumor growth along with increased infiltration of immune cells within the tumor in mouse models....
6.
Richert I, Berchard P, Abbes L, Novikov A, Chettab K, Vandermoeten A, et al.
Cancers (Basel)
. 2023 Sep;
15(18).
PMID: 37760603
Osteosarcoma (OsA) has limited treatment options and stagnant 5-year survival rates. Its immune microenvironment is characterized by a predominance of tumor-associated macrophages (TAMs), whose role in OsA progression remain unclear....
7.
Macauda A, Briem K, Clay-Gilmour A, Cozen W, Forsti A, Giaccherini M, et al.
Leukemia
. 2023 Sep;
37(11):2326-2329.
PMID: 37723249
No abstract available.
8.
Dumontet C, Reichert J, Senter P, Lambert J, Beck A
Nat Rev Drug Discov
. 2023 Jun;
22(8):641-661.
PMID: 37308581
Antibody-drug conjugates (ADCs) combine the specificity of monoclonal antibodies with the potency of highly cytotoxic agents, potentially reducing the severity of side effects by preferentially targeting their payload to the...
9.
Blangero F, Robert M, Andraud T, Dumontet C, Vidal H, Eljaafari A
Cancers (Basel)
. 2023 Jun;
15(11).
PMID: 37296927
Background: Obesity is a well-known risk factor for cancer. We have previously reported the role of adipose-tissue-derived mesenchymal stem cells from obese individuals (ob-ASC) in the promotion of pathogenic Th17...
10.
Clavero E, Sanchez-Maldonado J, Macauda A, Ter Horst R, Sampaio-Marques B, Jurczyszyn A, et al.
Int J Mol Sci
. 2023 May;
24(10).
PMID: 37239846
Multiple myeloma (MM) arises following malignant proliferation of plasma cells in the bone marrow, that secrete high amounts of specific monoclonal immunoglobulins or light chains, resulting in the massive production...