Chaoran Shi
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Explore the profile of Chaoran Shi including associated specialties, affiliations and a list of published articles.
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11
Citations
180
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Recent Articles
1.
Xu J, Shi C, Ding Y, Qin T, Li C, Yuan F, et al.
Adv Sci (Weinh)
. 2024 Sep;
11(43):e2406398.
PMID: 39340832
Reconstruction of the neurovascular unit is essential for the repair of spinal cord injury (SCI). Nonetheless, detailed documentation of specific vascular changes following SCI and targeted interventions for vascular treatment...
2.
Shi C, Xu J, Ding Y, Chen X, Yuan F, Zhu F, et al.
Theranostics
. 2024 Sep;
14(14):5662-5681.
PMID: 39310103
Spinal cord injury (SCI)-induced vascular damage causes ischemia and hypoxia at the injury site, which, in turn, leads to profound metabolic disruptions. The effects of these metabolic alterations on neural...
3.
Xu J, Shi C, Yuan F, Ding Y, Xie Y, Liu Y, et al.
Bioact Mater
. 2023 Nov;
32:427-444.
PMID: 37954465
Mitochondria are crucial in sustaining and orchestrating cellular functions. Capitalizing on this, we explored mitochondrial transplantation as an innovative therapeutic strategy for acute spinal cord injury (SCI). In our study,...
4.
Chen X, Shi C, He M, Xiong S, Xia X
Signal Transduct Target Ther
. 2023 Sep;
8(1):352.
PMID: 37709773
The endoplasmic reticulum (ER) functions as a quality-control organelle for protein homeostasis, or "proteostasis". The protein quality control systems involve ER-associated degradation, protein chaperons, and autophagy. ER stress is activated...
5.
Yuan F, Peng W, Yang Y, Xu J, Liu Y, Xie Y, et al.
J Neuroinflammation
. 2023 Jun;
20(1):156.
PMID: 37391774
Background: Macrophage in the spinal cord injury (SCI) area imparts a chronic pro-inflammation effect that challenges the recovery of SCI. Previously, endothelial progenitor cell-produced exosomes (EPC-EXOs) have been noticed to...
6.
Xu J, Ding Y, Shi C, Yuan F, Sheng X, Liu Y, et al.
Aging Dis
. 2023 Jun;
PMID: 37307830
Hemorrhage and immune cell infiltration are the main pathological features of spinal cord injury (SCI). Excessive iron deposition is caused by leaking hemosiderin which may over-activate ferroptosis pathways, resulting in...
7.
Jiang L, Wang X, Ma F, Wang X, Shi M, Yan Q, et al.
J Exp Clin Cancer Res
. 2022 Jun;
41(1):211.
PMID: 35765089
Background: Tumor cells exhibited phenotypic and molecular characteristics similar to their lineage progenitor cells. Liver developmental signaling pathways are showed to be associated with HCC development and oncogenesis. The similarities...
8.
Shi C, Kwong D, Li X, Wang X, Fang X, Sun L, et al.
Cancers (Basel)
. 2022 Jun;
14(12).
PMID: 35740546
Cancer stem cells (CSCs) are responsible for tumorigenesis, therapeutic resistance, and metastasis in hepatocellular cancer (HCC). Cancer/testis antigen Maelstrom (MAEL) is implicated in the formation of CSC phenotypes, while the...
9.
Sun L, Xi S, Zhou Z, Zhang F, Hu P, Cui Y, et al.
Oncogene
. 2021 Nov;
41(5):732-744.
PMID: 34845378
Hyperactivation of RAS/MAPK signaling is commonly observed in hepatocellular carcinoma (HCC). Gain-of-function mutations of canonical RAS genes, however, are rarely detected and it remains unclear how the activity of this...
10.
Wang X, Wang J, Tsui Y, Shi C, Wang Y, Zhang X, et al.
Nat Commun
. 2021 Mar;
12(1):1518.
PMID: 33750796
Growing evidences suggest that cancer stem cells exhibit many molecular characteristics and phenotypes similar to their ancestral progenitor cells. In the present study, human embryonic stem cells are induced to...