Changzhi Huang
Overview
Explore the profile of Changzhi Huang including associated specialties, affiliations and a list of published articles.
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Articles
43
Citations
589
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Recent Articles
1.
Shen H, Wang Z, Chen Y, Huang C, Xu L, Tong Y, et al.
Arch Toxicol
. 2025 Mar;
PMID: 40059124
Colorectal cancer remains a major cause of cancer mortality, with limited sensitivity in current diagnostics. Aberrant DNA methylation in expression-regulating sites shows biomarker potential, though few studies explore such methylation-based...
2.
Lu Y, Chen Y, Wang Z, Shen H, Xu L, Huang C, et al.
J Transl Med
. 2025 Mar;
23(1):282.
PMID: 40050872
Background: Cancer-associated fibroblasts (CAFs), known for facilitating the progression and metastasis of colorectal cancer (CRC), have become a promising therapeutic target. However, the significant heterogeneity of CAFs and their intricate...
3.
Huang C, Liu Z, Guo Y, Wang W, Yuan Z, Guan Y, et al.
Nucleic Acids Res
. 2024 Nov;
53(D1):D1526-D1535.
PMID: 39558175
Genomic, epigenomic and transcriptomic alterations are hallmarks of cancer cells, and are closely connected. Especially, epigenetic regulation plays a critical role in tumorigenesis and progression. The growing single-cell epigenome data...
4.
Chen Y, Shen H, Wang Z, Huang C, Zhang H, Shao Y, et al.
J Exp Clin Cancer Res
. 2024 Sep;
43(1):261.
PMID: 39267084
Background: Long-term accumulation of misfolded proteins leads to endoplasmic reticulum (ER) stress in colorectal cancer (CRC). However, the precise pathways controlling the decision between survival and apoptosis in CRC are...
5.
Li Z, Li X, Seebacher N, Liu X, Wu W, Yu S, et al.
Carcinogenesis
. 2024 Jul;
45(10):786-798.
PMID: 39082894
Osteosarcoma (OS) is a bone malignant tumor affecting children, adolescents, and young adults. Currently, osteosarcoma is treated with chemotherapy regimens established over 40 years ago. The investigation of novel therapeutic...
6.
Huang C, Lu J, Yang J, Wang Z, Hang D, Fu Z
Front Mol Biosci
. 2024 May;
11:1209349.
PMID: 38725873
Purpose: Cystatin C (CysC), beyond its biomarker role of renal function, has been implicated in various physical and pathological activities. However, the impact of serum CysC on cancer mortality in...
7.
Shen H, Chen Y, Xu M, Zhou J, Huang C, Wang Z, et al.
Arch Toxicol
. 2024 Mar;
98(5):1499-1513.
PMID: 38480537
Cell senescence genes play a vital role in the pathogenesis of colorectal cancer, a process that may involve the triggering of genetic variations and reversible phenotypes caused by epigenetic modifications....
8.
Shao Y, Wang Z, Wu J, Lu Y, Chen Y, Zhang H, et al.
Funct Integr Genomics
. 2023 Oct;
23(4):316.
PMID: 37789099
Immunogenic cell death (ICD), a type of cell death that activates the tumor-specific immune response and thus exerts anti-tumor effects, is an emerging target in tumor therapy, but research on...
9.
Knockdown of UBQLN1 Functions as a Strategy to Inhibit CRC Progression through the ERK-c-Myc Pathway
Ni R, Jiang J, Zhao M, Huang S, Huang C
Cancers (Basel)
. 2023 Jun;
15(12).
PMID: 37370699
Purpose: Colorectal cancer (CRC) is characterized by the absence of obvious symptoms in the early stage. Due to the high rate of late diagnosis of CRC patients, the mortality rate...
10.
Lin H, Ni R, Li D, Zhao M, Li Y, Li K, et al.
Int J Med Sci
. 2023 Jun;
20(7):933-942.
PMID: 37324190
Long non-coding RNAs are thought to play a vital role in a variety of human malignancies. Studies have shown that MIR155 host gene (MIR155HG) acts as an oncogene in several...