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Changhong Du

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Articles 34
Citations 439
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Recent Articles
11.
Zhang W, Wei X, Yang S, Du C, Hu B
Medicine (Baltimore) . 2022 Nov; 101(46):e31948. PMID: 36401460
Background: Two systematic reviews summarized the efficacy and safety of pharmacological prophylaxis for venous thromboembolism (VTE) after hepatic resection, but both lacked a discussion of the differences in the pharmacological...
12.
Lan Q, Du C, Xiong J, Wu Y, Liao W, Liu C, et al.
J Thromb Haemost . 2022 Sep; 20(12):2972-2987. PMID: 36087344
Background: Thrombosis and hemorrhage as two opposite pathologies are prevalent within the chronic kidney disease (CKD) population. Platelet homeostasis, which positions centrally in their pathogenesis, varies among the CKD population,...
13.
Han W, Du C, Zhu Y, Ran L, Wang Y, Xiong J, et al.
JACC Basic Transl Sci . 2022 Sep; 7(8):820-840. PMID: 36061341
Chronic kidney disease (CKD) is well recognized as a distinct contributor to cardiac hypertrophy, while the underlying mechanism remains incompletely understood. Here, the authors show that myocardial mitochondrial oxidative damage...
14.
Wu Y, Liao W, Chen J, Liu C, Zhang S, Yu K, et al.
Nutrients . 2022 Aug; 14(16). PMID: 36014901
Myelosuppression is a common and intractable side effect of cancer therapies including radiotherapy and chemotherapy, while the underlying mechanism remains incompletely understood. Here, using a mouse model of radiotherapy-induced myelosuppression,...
15.
Du C, Wang X, Wu Y, Liao W, Xiong J, Zhu Y, et al.
Cell Rep . 2022 Feb; 38(7):110392. PMID: 35172146
The composition and origin of extrinsic cues required for hematopoietic stem cell (HSC) maintenance are incompletely understood. Here we identify renal Klotho and inorganic phosphate (Pi) as extrinsic factors that...
16.
Wang X, Liao W, Chen J, Wu Y, Liu C, Chen S, et al.
Exp Cell Res . 2021 Nov; 409(2):112934. PMID: 34801561
Hematopoietic stem cells (HSCs) are sensitive to ionizing radiation (IR) damage, and its injury is the primary cause of bone marrow (BM) hematopoietic failure and even death after exposure to...
17.
Han S, Zhao G, Wei Z, Chen Y, Zhao J, He Y, et al.
Peptides . 2021 Aug; 145:170638. PMID: 34419496
The ongoing coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is a global concern and necessitates efficient drug antagonists. Angiotensin-converting enzyme-2 (ACE2) is...
18.
Bi X, Du C, Wang X, Wang X, Han W, Wang Y, et al.
Adv Sci (Weinh) . 2021 Mar; 8(5):2002738. PMID: 33717842
Chronic kidney disease (CKD) is associated with accelerated atherosclerosis progression and high incidence of cardiovascular events, hinting that atherosclerotic plaques in CKD may be vulnerable. However, its cause and mechanism...
19.
Liao W, Du C, Wang J
Front Immunol . 2020 Dec; 11:573915. PMID: 33329537
Cytosolic DNA sensing is a fundamental mechanism by which organisms handle various stresses, including infection and genotoxicity. The hematopoietic system is sensitive to stresses, and hematopoietic changes are often rapid...
20.
Huang Y, Wang S, Zhou J, Liu Y, Du C, Yang K, et al.
Nat Commun . 2020 Sep; 11(1):4664. PMID: 32938919
Cardiorenal syndrome type 4 (CRS4) is a common complication of chronic kidney disease (CKD), but the pathogenic mechanisms remain elusive. Here we report that morphological and functional changes in myocardial...