Chang-Rong Chen
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Explore the profile of Chang-Rong Chen including associated specialties, affiliations and a list of published articles.
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22
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Recent Articles
1.
Chen C, Briggs L, Koelker M, Stone B, Alkhatib K, Labban M, et al.
Prostate Int
. 2024 Dec;
12(4):207-212.
PMID: 39735196
Background: The impact of behavioral habits such as exercise on the physical health of prostate cancer (PCa) patients is poorly understood. We aimed to investigate PCa patients' exercise habits and...
2.
Peng C, Chen E, Chen C, Chyau C, Chen K, Peng R
PLoS One
. 2024 Oct;
19(10):e0306575.
PMID: 39413106
Patients with chronic kidney disease (CKD) have a high incidence of dyslipidemia comprising high triglyceride (TG) and low high-density lipoprotein (HDL)-cholesterol levels. An abnormal increase of TGs within cells can...
3.
Chen K, Dhar T, Chen C, Chen E, Peng C
Biochim Biophys Acta Mol Basis Dis
. 2024 Mar;
1870(4):167106.
PMID: 38428685
Bladder cancer (BLCA) is one of the most prevalent malignancies worldwide with a high mortality rate and poor response to immunotherapy in patients expressing lower programmed death ligand 1 (PD-L1)...
4.
Labban M, Chen C, Frego N, Nguyen D, Lipsitz S, Reich A, et al.
JAMA Netw Open
. 2023 Jul;
6(7):e2325291.
PMID: 37498602
Importance: Geographic access, including mode of transportation, to health care facilities remains understudied. Objective: To identify sociodemographic factors associated with public vs private transportation use to access health care and...
5.
Labban M, Frego N, Qian Z, Nguyen D, Chen C, Berk B, et al.
World J Urol
. 2022 Sep;
40(11):2649-2656.
PMID: 36125504
Purpose: To assess whether the 5-item Frailty Index (5i-FI) predicts surgical complications of endoscopic surgery for benign prostatic obstruction (BPO) and examine the rates of these complications across BPO surgical...
6.
Peng C, Chen C, Chen C, Chen K, Peng R
Chem Biol Interact
. 2022 Feb;
356:109858.
PMID: 35151640
Bicalutamide (Bic), frequently used in androgen-deprivation therapy for treating prostate cancer, was demonstrated to induce multiple apoptosis and fibrosis pathways and mitochondrial dysfunction in renal mesangial cells. Whether Bic also...
7.
Chen K, Chen C, Chen C, Peng C, Peng R
J Clin Med
. 2022 Jan;
11(1).
PMID: 35011880
Bicalutamide (Bic) is an androgen deprivation therapy (ADT) for treating prostate cancer, while ADT is potentially associated with acute kidney injury. Previously, we recognized Bic induced renal mitochondria dysfunction in...
8.
Lin Y, Wang J, Wu M, Lin Y, Chen C, Chen C, et al.
Int J Mol Sci
. 2020 Jun;
21(12).
PMID: 32575412
Dysregulation of fatty acid oxidation and accumulation of fatty acids can cause kidney injury. Nifedipine modulates lipogenesis-related transcriptional factor SREBP-1/2 in proximal tubular cells by inhibiting the Adenosine 5'-monophosphate (AMP)-activated...
9.
Chen K, Chen C, Chen C, Tzou K, Peng C, Peng R
Int J Mol Sci
. 2020 May;
21(9).
PMID: 32403414
Combined androgen blockade using bicalutamide (Bic) is a therapeutic choice for treating prostate cancer (PCa). However, even at regular clinical dosages, Bic frequently shows adverse effects associated with cardiovascular and...
10.
Peng C, Chen C, Chen C, Lin Y, Chen K, Peng R
Int J Mol Sci
. 2020 May;
21(9).
PMID: 32365658
Nifedipine (NF) is reported to have many beneficial effects in antihypertensive therapy. Recently, we found that NF induced lipid accumulation in renal tubular cells. Palmitic acid-induced renal lipotoxicity was found...