Chang-Joon Lee
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Explore the profile of Chang-Joon Lee including associated specialties, affiliations and a list of published articles.
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23
Citations
122
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Recent Articles
1.
Gazzard S, Cullen-McEwen L, Nikulina M, Clever A, Gardner B, Smith D, et al.
Anat Rec (Hoboken)
. 2024 Sep;
PMID: 39238265
Fibrosis and loss of functional capillary surface area may contribute to renal tissue hypoxia in a range of kidney diseases. However, there is limited quantitative information on the impact of...
2.
Smith D, Azadi A, Lee C, Gardiner B
Tissue Barriers
. 2022 Aug;
11(3):2110798.
PMID: 35959954
The glomerular basement membrane (GBM) is an important tissue structure in kidney function. It is the membrane through which filtrate and solutes must pass to reach the nephron tubules. This...
3.
Umugire A, Lee S, Lee C, Choi Y, Kim T, Cho H
Clin Exp Otorhinolaryngol
. 2022 Apr;
15(3):220-229.
PMID: 35413171
Objectives: Hyaluronan synthase 1 (HAS1) is a membrane-bound protein that is abundant in the epidermis and dermis, and it is important for skin function. However, its association with hearing loss...
4.
Lee C, Gardiner B, Evans R, Smith D
Am J Physiol Renal Physiol
. 2021 Aug;
321(4):F527-F547.
PMID: 34459223
Continuous measurement of bladder urine oxygen tension (Po) is a method to potentially detect renal medullary hypoxia in patients at risk of acute kidney injury (AKI). To assess its practicality,...
5.
Smith D, Lee C, Gardiner B
PLoS One
. 2020 Aug;
15(8):e0238146.
PMID: 32841295
We have previously developed a new theory for pressure dependent outflow from the human eye, and tested the model using experimental data at intraocular pressures above normal eye pressures. In...
6.
Lee C, Gardiner B, Smith D
Comput Biol Med
. 2020 Apr;
119:103676.
PMID: 32339121
Acute kidney injury (AKI) is a major complication following cardiac surgery requiring cardiopulmonary bypass (CPB). It is likely that poor renal perfusion contributes to the occurrence of AKI, via renal...
7.
Smith D, Lee C, Gardiner B
Prog Retin Eye Res
. 2020 Feb;
:100845.
PMID: 32035123
When analyzing vitreal drug delivery, or the pharmacological effects of drugs on intraocular pressure, or when interpreting outflow facility measurements, it is generally accepted that the fluid in the vitreous...
8.
Gardiner B, Smith D, Lee C, Ngo J, Evans R
Acta Physiol (Oxf)
. 2020 Feb;
228(4):e13450.
PMID: 32012449
Computational models have made a major contribution to the field of physiology. As the complexity of our understanding of biological systems expands, the need for computational methods only increases. But...
9.
Evans R, Smith D, Lee C, Ngo J, Gardiner B
Anat Rec (Hoboken)
. 2019 Oct;
303(10):2544-2552.
PMID: 31566903
Per gram of tissue, the kidneys are among our most highly perfused organs. Yet the renal cortex and, in particular, the renal medulla are susceptible to hypoxia. In turn, hypoxia...
10.
Lee C, Gardiner B, Evans R, Smith D
Am J Physiol Renal Physiol
. 2019 Sep;
317(6):F1483-F1502.
PMID: 31482732
We have previously developed a three-dimensional computational model of oxygen transport in the renal medulla. In the present study, we used this model to quantify the sensitivity of renal medullary...