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Jennifer P Ngo

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Citations 180
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Recent Articles
1.
Noe K, Don A, Cochrane A, Zhu M, Ngo J, Smith J, et al.
Clin Exp Pharmacol Physiol . 2023 Aug; 50(11):878-892. PMID: 37549882
Targeting greater pump flow and mean arterial pressure (MAP) during cardiopulmonary bypass (CPB) could potentially alleviate renal hypoxia and reduce the risk of postoperative acute kidney injury (AKI). Therefore, in...
2.
Vogiatjis J, Noe K, Don A, Cochrane A, Zhu M, Smith J, et al.
J Cardiothorac Vasc Anesth . 2022 Nov; 37(2):237-245. PMID: 36435720
Objectives: To determine if the administration of norepinephrine to patients recovering from on-pump cardiac surgery is associated with changes in urinary oxygen tension (PO), an indirect index of renal medullary...
3.
Noe K, Ngo J, Martin A, Zhu M, Cochrane A, Smith J, et al.
Clin Exp Pharmacol Physiol . 2021 Oct; 49(2):228-241. PMID: 34674291
Acute kidney injury (AKI) is a common and serious post-operative complication of cardiac surgery. The value of a predictive biomarker is determined not only by its predictive efficacy, but also...
4.
Ngo J, Noe K, Zhu M, Martin A, Ollason M, Cochrane A, et al.
J Card Surg . 2021 Jul; 36(10):3577-3585. PMID: 34327740
Background: Acute kidney injury (AKI) is common after cardiac surgery requiring cardiopulmonary bypass. Renal hypoxia may precede clinically detectable AKI. We compared the efficacy of two indices of renal hypoxia,...
5.
Evans R, Cochrane A, Hood S, Iguchi N, Marino B, Bellomo R, et al.
Perfusion . 2021 May; 37(6):624-632. PMID: 33977810
Introduction: The renal medulla is susceptible to hypoxia during cardiopulmonary bypass (CPB), which may contribute to the development of acute kidney injury. But the speed of onset of renal medullary...
6.
Pearson J, Thambyah H, Waddingham M, Inagaki T, Sukumaran V, Ngo J, et al.
Clin Sci (Lond) . 2021 Jan; 135(2):327-346. PMID: 33480422
A high salt intake exacerbates insulin resistance, evoking hypertension due to systemic perivascular inflammation, oxidative-nitrosative stress and endothelial dysfunction. Angiotensin-converting enzyme inhibitor (ACEi) and angiotensin receptor blockers (ARBs) have been...
7.
Gardiner B, Smith D, Lee C, Ngo J, Evans R
Acta Physiol (Oxf) . 2020 Feb; 228(4):e13450. PMID: 32012449
Computational models have made a major contribution to the field of physiology. As the complexity of our understanding of biological systems expands, the need for computational methods only increases. But...
8.
Evans R, Smith D, Lee C, Ngo J, Gardiner B
Anat Rec (Hoboken) . 2019 Oct; 303(10):2544-2552. PMID: 31566903
Per gram of tissue, the kidneys are among our most highly perfused organs. Yet the renal cortex and, in particular, the renal medulla are susceptible to hypoxia. In turn, hypoxia...
9.
Ow C, Ullah M, Ngo J, Sayakkarage A, Evans R
Am J Physiol Renal Physiol . 2019 Jun; 317(2):F322-F332. PMID: 31188031
Pimonidazole adduct immunohistochemistry is one of the few available methods for assessing renal tissue hypoxia at the cellular level. It appears to be prone to artifactual false positive staining under...
10.
Ngo J, Lankadeva Y, Zhu M, Martin A, Kanki M, Cochrane A, et al.
Acta Physiol (Oxf) . 2019 May; 227(1):e13294. PMID: 31066975
Aim: Urinary oxygen tension (uPO ) may provide an estimate of renal medullary PO (mPO ) and thus risk of acute kidney injury (AKI). We assessed the potential for variations...