Chang-Han Chen
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Explore the profile of Chang-Han Chen including associated specialties, affiliations and a list of published articles.
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77
Citations
915
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Recent Articles
1.
Tsai M, Chen C, Chen C, Lee M, Wu L, Hsu Y, et al.
Curr Issues Mol Biol
. 2025 Feb;
47(2).
PMID: 39996849
Colorectal cancer (CRC) is a common cancer globally, and chemotherapy often causes severe complications, necessitating effective drugs with minimal side effects. As L. extract (ACE) is a Traditional Chinese Medicine...
2.
Li S, Huang W, Chen Y, Lu H, Lo C, Tsai H, et al.
Cancer Cell Int
. 2024 Dec;
24(1):425.
PMID: 39710692
Introduction: Chronic alcohol consumption and tobacco usage are major risk factors for esophageal squamous cell carcinoma (ESCC). Excessive tobacco and alcohol consumption lead to oxidative stress and the generation of...
3.
Huang Y, Chiu L, Tseng J, Hsu K, Chen C, Sheu G, et al.
Int J Mol Sci
. 2024 Jan;
25(1).
PMID: 38203787
Lung cancer is considered the number one cause of cancer-related deaths worldwide. Although current treatments initially reduce the lung cancer burden, relapse occurs in most cases; the major causes of...
4.
Chen C, Lin H, Huang M, Chiang C, Lee K, Phuong N, et al.
BMC Mol Cell Biol
. 2024 Jan;
25(1):2.
PMID: 38172660
Background: Fas-associated factor 1 (FAF1) is a multidomain protein that interacts with diverse partners to affect numerous cellular processes. Previously, we discovered two Small Ubiquitin-like Modifier (SUMO)-interacting motifs (SIMs) within...
5.
Chiu T, Chen C, Chen Y, Wee Y, Wang C, Luo S
Cancer Cell Int
. 2023 Sep;
23(1):212.
PMID: 37743493
Background: Research studies have demonstrated that Midkine (MDK) can influence the expression and activity of Renin-angiotensin system (RAS) components. Angiotensin II is involved in tumor growth and angiogenesis in different...
6.
Wang B, Chang Y, Shiu L, Lee Y, Lin Y, Hsu Y, et al.
Comput Struct Biotechnol J
. 2023 Sep;
21:4030-4043.
PMID: 37664175
Esophageal squamous cell carcinoma (ESCC), one of the most lethal cancers, has become a global health issue. Stearoyl-coA desaturase 1 (SCD1) has been demonstrated to play a crucial role in...
7.
Li S, Qian L, Chen Y, Lu H, Tsai H, Lyu H, et al.
J Cell Physiol
. 2022 Jul;
237(9):3671-3686.
PMID: 35861939
Myosin-related proteins play an important role in cancer progression. However, the clinical significance, biological functions, and mechanisms of myosin 1B (MYO1B), in esophageal squamous cell carcinoma (ESCC) remain unclear. The...
8.
Chen Y, Chen C, Chien C, Su Y, Luo S, Li S
PeerJ
. 2022 Jul;
10:e13759.
PMID: 35855897
Background: Jumonji domain-containing-3 (JMJD3) is reported to be a histone H3 lysine 27 (H3K27) demethylase and a tumor suppressor gene. The present study designed to investigate the crucial role of...
9.
Aberrant miR-874-3p/leptin/EGFR/c-Myc signaling contributes to nasopharyngeal carcinoma pathogenesis
Luo S, Tsai H, Hwang C, Chiu T, Li S, Hsu Y, et al.
J Exp Clin Cancer Res
. 2022 Jul;
41(1):215.
PMID: 35778755
Background: Leptin is important in physiological and pathological functions in various cancers, however, the significance and mechanisms of leptin in nasopharyngeal carcinoma remain ambiguous. Methods: Leptin expression was analyzed by...
10.
Lin H, Shen T, Chen P, Chen T, Yeh J, Tsou S, et al.
Biochem Biophys Res Commun
. 2022 Jun;
617(Pt 2):11-17.
PMID: 35689837
Exposure to particulate matter 2.5 (PM2.5) has been linked to ocular surface diseases, yet knowledge of the molecular mechanism impacted on retina pathogenesis is limited. Therefore, the purpose of this...