Chang-Han Chen
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Explore the profile of Chang-Han Chen including associated specialties, affiliations and a list of published articles.
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77
Citations
915
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Recent Articles
11.
Luo S, Tsai H, Chiu T, Li S, Hsu Y, Su L, et al.
Int J Mol Sci
. 2022 May;
23(10).
PMID: 35628510
Leptin is a crucial regulator of metabolism and energy homeostasis in mammals. Many studies have investigated the impacts of leptin on human cancers, such as proliferation and metastasis. However, the...
12.
Huang T, Chang C, Chien C, Huang G, Chen Y, Su L, et al.
Mol Oncol
. 2022 Mar;
16(13):2585-2606.
PMID: 35313071
Abnormal DRP1 expression has been identified in a variety of human cancers. However, the prognostic potential and mechanistic role of DRP1 in head and neck cancer (HNC) are currently poorly...
13.
Chiu T, Chen Y, Lan J, Chen Y, Chen Y, Lin H, et al.
Am J Cancer Res
. 2021 Dec;
11(11):5609-5624.
PMID: 34873483
Pancreatic ductal adenocarcinoma (PDAC), one of the most deadly digestive cancers, has a poor 5-year survival rate and is resistant to chemotherapeutic agents, such as gemcitabine. Notch3 plays an important...
14.
Chen Y, Chen C, Chien C, Su Y, Luo S, Li S
BMC Cancer
. 2021 Sep;
21(1):979.
PMID: 34465286
Background: Ubiquitously transcribed tetratricopeptide repeat on chromosome X (UTX) has been identified as a histone 3 lysine 27 (H3K27) demethylase and acted as a tumor suppressor gene or oncogenic function....
15.
Luo S, Wu S, Chen W, Wu C, Chiu T, Yang Y, et al.
Sci Rep
. 2021 Aug;
11(1):17161.
PMID: 34433896
Oral squamous cell carcinoma (OSCC) remains one of the most challenging clinical problems in the field due to its high rate of locoregional and distant metastases. However, studies that assess...
16.
Yang W, Chen C, Jia M, Xing X, Gao L, Tsai H, et al.
Front Cell Dev Biol
. 2021 Mar;
9:641270.
PMID: 33681225
Important evidence indicates the microbiota plays a key role in esophageal squamous cell carcinoma (ESCC). The esophageal microbiota was prospectively investigated in 18 patients with ESCC and 11 patients with...
17.
Chen C, Su L, Tsai H, Hwang C
Cancer Manag Res
. 2019 Jul;
11:5243-5254.
PMID: 31289447
Nasopharyngeal carcinoma (NPC) is a prevalent malignant tumor in Southeast Asia. The management of NPC has remained a challenge until now. ELF-1 is a member of the ETS family of...
18.
Wang C, Hung P, Chiang C, Lombes M, Chen C, Lee K, et al.
Biochim Biophys Acta Mol Cell Res
. 2019 Apr;
1866(8):1282-1297.
PMID: 30935967
Fas-associated factor 1 (FAF1) was originally isolated as a Fas-associated factor and was subsequently found to interact with numerous other proteins that are involved in various cellular events including Fas-mediated...
19.
Li S, Lu H, Chen Y, Lo C, Huang W, Tien W, et al.
Surgery
. 2019 Jan;
165(5):946-952.
PMID: 30678869
Background: The Jumonji-domain containing 3 has diverse roles in multiple cancers. Here, we investigated its prognostic significance in esophageal squamous cell carcinoma. Methods: By using immunohistochemistry, the Jumonji-domain containing 3...
20.
Li S, Lu H, Huang W, Chen Y, Lo C, Lan Y, et al.
Cancer Cell Int
. 2019 Jan;
18:219.
PMID: 30618491
Background: ESPN (Espin), an actin filament-binding protein, plays an important role in regulating the organization, dimensions, dynamics, and signaling capacities of the actin filament-rich, microvillus-type specializations that mediate sensory transduction...