Chang-Chun Ling
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Explore the profile of Chang-Chun Ling including associated specialties, affiliations and a list of published articles.
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Articles
84
Citations
1016
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Recent Articles
1.
2.
Sun T, Wang S, Liu X, Ji D, Xie X, Yang R, et al.
J Photochem Photobiol B
. 2025 Mar;
265:113135.
PMID: 40022995
Photodynamic therapy (PDT) is an emerging therapeutic modality to selectively eradicate pathological cells, such as cancer cells. Hence, we designed and synthesized a series of novel ꞵ-carboline/cyanoisoflavone photosensitizers A1-A3. All...
3.
Randhawa G, Mobarakabadi M, DMello C, Morch M, Zhang P, Ling C, et al.
J Neuroimmunol
. 2025 Jan;
400:578533.
PMID: 39864280
The extracellular matrix (ECM) plays an important role in the central nervous system (CNS), shaping tissue structure and functions as well as contributing to the pathology of chronic diseases such...
4.
Li H, Ghorbani S, Oladosu O, Zhang P, Visser F, Dunn J, et al.
J Neuroinflammation
. 2025 Jan;
22(1):2.
PMID: 39755654
Background: Intracerebral hemorrhage (ICH) causes prominent deposition of extracellular matrix molecules, particularly the chondroitin sulphate proteoglycan (CSPG) member neurocan. In tissue culture, neurocan impedes the properties of oligodendrocytes. Whether therapeutic...
5.
Che A, Ghaseminezhad H, Zellmann-Parrotta C, Duong J, Williams V, Ling C
Molecules
. 2024 Dec;
29(23).
PMID: 39683792
This study explores the liquid crystalline properties of novel amphiphilic β-cyclodextrin derivatives functionalized with seven oligoethylene glycol chains at the primary face, terminated with either an O-methyl or an O-cyanoethyl...
6.
Zhang P, Barbot C, Gandikota R, Li C, Gouriou L, Gouhier G, et al.
Molecules
. 2024 Oct;
29(19).
PMID: 39407616
Sucrose constitutes a non-toxic, biodegradable, low-cost and readily available natural product. To expand its utility, we developed total synthesis for a ligand based on a sucrose scaffold for potential use...
7.
Espejo J, Zellmann-Parrotta C, Sarkar D, Che A, Michaelis V, Williams V, et al.
Chemistry
. 2024 Oct;
30(72):e202403232.
PMID: 39382344
Amphiphilic supramolecular materials based on biodegradable cyclodextrins (CDs) have been known to self-assemble into different types of thermotropic liquid crystals, including smectic and hexagonal columnar mesophases. Previous studies on amphiphilic...
8.
Beddows C, Shi F, Horton A, Dalal S, Zhang P, Ling C, et al.
Nature
. 2024 Sep;
633(8031):914-922.
PMID: 39294371
Metabolic diseases such as obesity and type 2 diabetes are marked by insulin resistance. Cells within the arcuate nucleus of the hypothalamus (ARC), which are crucial for regulating metabolism, become...
9.
Che A, Espejo J, Ling C
Molecules
. 2024 Jun;
29(12).
PMID: 38930780
In this study, we report a novel per-6-substituted β-cyclodextrin () featuring seven phosphoramidate moieties as an innovative host for inclusion. This structurally well-defined host has remarkable water solubility and was...
10.
Homayonia S, Ling C
Chemistry
. 2024 Jan;
30(12):e202303753.
PMID: 38215247
The enzyme-resistant thioglycosides are highly valuable immunogens because of their enhanced metabolic stability. We report the first synthesis of a family of thiooligosaccharides related to the capsular polysaccharides (CPS) of...