Chandrashekhar S Patil
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Explore the profile of Chandrashekhar S Patil including associated specialties, affiliations and a list of published articles.
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23
Citations
162
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Recent Articles
11.
Singh V, Patil C, Kulkarni S
Pharmacol Rep
. 2005 Jun;
57(3):380-4.
PMID: 15985722
Hyperalgesia from an incisional pain is evoked by noxious stimuli (mechanical and cold). The present study was aimed to examine the effect of licofelone, a dual inhibitor of cyclooxygenases (COX-1/COX-2)...
12.
Singh V, Patil C, Kulkarni S
Pharmacol Biochem Behav
. 2005 Jun;
81(3):433-9.
PMID: 15935457
Pain is commonly associated with inflammation. Several mediators including prostaglandins have been implicated in pain and inflammation. However, the recent reports indicated the role of leukotrienes as signaling molecules in...
13.
Singh V, Patil C, Kulkarni S
Indian J Exp Biol
. 2005 Apr;
43(3):247-53.
PMID: 15816411
The present study was aimed to evaluate the effect of licofelone, a dual inhibitor of cycloxygenase1/2-5-lipoxygenase against indomethacin-induced gastric damage in rats and mice in order to assess the role...
14.
Patil C, Singh V, Jain N, Kulkarni S
Indian J Exp Biol
. 2005 Mar;
43(2):167-71.
PMID: 15782818
Nitric oxide (NO) is an important neurotransmitter in the gut and has been demonstrated to be a key physiological mediator of non-adrenergic non-cholinergic (NANC) relaxation of gastrointestinal smooth muscle. In...
15.
Patil C, Singh V, Singh S, Kulkarni S
Pharmacology
. 2004 Sep;
72(3):190-5.
PMID: 15452368
Diabetic neuropathy is one of the most frequent peripheral neuropathies associated with hyperalgesia and hyperesthesia. Besides alteration in the levels of neurotransmitter, alteration in the neuronal nitric oxide synthase (nNOS)...
16.
Singh V, Patil C, Kulkarni S
Indian J Exp Biol
. 2004 Sep;
42(7):667-73.
PMID: 15339030
Leukotrienes play a part in inflammatory response. The unique role of the enzyme 5-lipoxygenase (5-LOX) in the production of leukotrienes makes it a likely therapeutic target for inflammatory conditions like...
17.
Singh V, Patil C, Jain N, Kulkarni S
Pharmacology
. 2004 Aug;
72(2):77-84.
PMID: 15331912
The objective of the present study was to determine the effect of a selective cyclooxygenase-2 (COX-2) inhibitor in in-vivo dextran sodium sulfate (DSS)-stimulated distal colon tissues of the rat. Longitudinal...
18.
Singh V, Patil C, Kulkarni S
Inflammopharmacology
. 2004 Jul;
12(2):189-95.
PMID: 15265319
Arachidonic acid metabolites, prostaglandins and leukotrienes are detected in clinical cases of herniated nucleus pulposus. However, little is known about their role in the associated symptoms like radicular pain. The...
19.
Kulkarni S, Patil C, Jain N, Singh A
Indian J Exp Biol
. 2004 Jul;
42(6):567-9.
PMID: 15260106
Biliary, ureteric and intestinal colic are extremely common clinical conditions associated with smooth muscle spasm. In the present study, antispasmodic activity was carried out against acetylcholine (10-640 ng/ml)-induced contractions on...
20.
Patil C, Jain N, Singh V, Kulkarni S
Indian J Exp Biol
. 2004 Apr;
42(4):361-7.
PMID: 15088685
Acetylcholine and cholinomimetic agents with predominant muscarinic action are known to increase the concentration of cGMP by activation of nitric oxide signaling pathway in the nociceptive conditions. The present study...