Chakrabhavi D Mohan
Overview
Explore the profile of Chakrabhavi D Mohan including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
143
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Recent Articles
1.
Suresh R, Jung Y, Mohan C, Gowda S, Harsha K, Mantelingu K, et al.
Drug Dev Res
. 2023 Sep;
84(8):1724-1738.
PMID: 37756467
Signal transducer and activator of transcription 3 (STAT3) and STAT5 are the transcription factors that have been studied extensively in relevance to the development of cancers in humans. Suppression of...
2.
Ashrafizadeh M, Mohan C, Rangappa S, Zarrabi A, Hushmandi K, Kumar A, et al.
Med Res Rev
. 2023 Mar;
43(5):1263-1321.
PMID: 36951271
Gastrointestinal (GI) tumors (cancers of the esophagus, gastric, liver, pancreas, colon, and rectum) contribute to a large number of deaths worldwide. STAT3 is an oncogenic transcription factor that promotes the...
3.
Siddaiah C, Kumar Bm A, Deepak S, Lateef S, Nagpal S, Rangappa K, et al.
Cells
. 2020 Dec;
10(1).
PMID: 33374892
There is an urge for traditional herbal remedies as an alternative to modern medicine in treating several ailments. is one such plant, used traditionally to treat several diseases. In several...
4.
Hari S, Swaroop T, Preetham H, Mohan C, Muddegowda U, Basappa S, et al.
Curr Org Synth
. 2020 Feb;
17(3):243-250.
PMID: 32096746
Design of chemically novel, biologically potent small heterocyclic molecules with anticancer activities, which targets the enzyme heparanase has gained prominent clinical interest. We have synthesized a novel class of carboxamide...
5.
Uzma F, Mohan C, Hashem A, Konappa N, Rangappa S, Kamath P, et al.
Front Pharmacol
. 2018 May;
9:309.
PMID: 29755344
Cancer is a major cause of death worldwide, with an increasing number of cases being reported annually. The elevated rate of mortality necessitates a global challenge to explore newer sources...
6.
Rakesh K, Jagadish S, Swaroop T, Mohan C, Ashwini N, Harsha K, et al.
Med Chem
. 2014 Dec;
11(5):462-72.
PMID: 25494807
2,4-Disubstituted thiophene derivatives were synthesized and assessed for antiinflammatory and anti-cancer activities by targeting two important enzymes of the arachidonic acid metabolism. Both lipoxygenase and cyclooxygenase enzymes play vital role...
7.
Keerthy H, Garg M, Mohan C, Madan V, Kanojia D, Shobith R, et al.
PLoS One
. 2014 Oct;
9(9):e107118.
PMID: 25268519
The anti-apoptotic protein Bcl-2 is a well-known and attractive therapeutic target for cancer. In the present study the solution-phase T3P-DMSO mediated efficient synthesis of 2-amino-chromene-3-carbonitriles from alcohols, malanonitrile and phenols...
8.
Rakesh K, Jagadish S, Vinayaka A, Hemshekhar M, Paul M, Thushara R, et al.
PLoS One
. 2014 Sep;
9(9):e107182.
PMID: 25238069
Thrombocytopenia is a serious issue connected with the pathogenesis of several human diseases including chronic inflammation, arthritis, Alzheimer's disease, cardiovascular diseases (CVDs) and other oxidative stress-associated pathologies. The indiscriminate use...