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Chakit Arora

Explore the profile of Chakit Arora including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 165
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Recent Articles
1.
Carli F, Di Chiaro P, Morelli M, Arora C, Bisceglia L, De Oliveira Rosa N, et al.
Nat Commun . 2025 Feb; 16(1):1654. PMID: 39952993
High-throughput screening of drug sensitivity of cancer cell lines (CCLs) holds the potential to unlock anti-tumor therapies. In this study, we leverage such datasets to predict drug response using cell...
2.
Arora C, Matic M, Bisceglia L, Di Chiaro P, De Oliveira Rosa N, Carli F, et al.
Cell Genom . 2024 May; 4(5):100557. PMID: 38723607
We explored the dysregulation of G-protein-coupled receptor (GPCR) ligand systems in cancer transcriptomics datasets to uncover new therapeutics opportunities in oncology. We derived an interaction network of receptors with ligands...
3.
Arora C, De Oliveira Rosa N, Matic M, Cascone M, Miglionico P, Raimondi F
Bioinform Adv . 2023 Oct; 3(1):vbad135. PMID: 37810457
Summary: EXPANSION (https://expansion.bioinfolab.sns.it/) is an integrated web-server to explore the functional consequences of protein-coding alternative splice variants. We combined information from Differentially Expressed (DE) protein-coding transcripts from cancer genomics, together...
4.
Arora C, Matic M, DiChiaro P, De Oliveira Rosa N, Carli F, Clubb L, et al.
bioRxiv . 2023 Jul; PMID: 37398064
We explored the dysregulation of GPCR ligand signaling systems in cancer transcriptomics datasets to uncover new therapeutics opportunities in oncology. We derived an interaction network of receptors with ligands and...
5.
Pande A, Patiyal S, Lathwal A, Arora C, Kaur D, Dhall A, et al.
J Comput Biol . 2022 Oct; 30(2):204-222. PMID: 36251780
In the last three decades, a wide range of protein features have been discovered to annotate a protein. Numerous attempts have been made to integrate these features in a software...
6.
Kaur D, Patiyal S, Arora C, Singh R, Lodhi G, Raghava G
Front Immunol . 2021 Dec; 12:780610. PMID: 34880873
Defensins are host defense peptides present in nearly all living species, which play a crucial role in innate immunity. These peptides provide protection to the host, either by killing microbes...
7.
Arora C, Kaur D, Naorem L, Raghava G
PLoS One . 2021 Nov; 16(11):e0259534. PMID: 34767591
Aberrant expressions of apoptotic genes have been associated with papillary thyroid carcinoma (PTC) in the past, however, their prognostic role and utility as biomarkers remains poorly understood. In this study,...
8.
Arora C, Kaur D, Raghava G
Proteomics . 2021 Oct; 22(3):e2000311. PMID: 34637591
Numerous cancer-specific prognostic models have been developed in the past, wherein one model is applicable for only one type of cancer. In this study, an attempt has been made to...
9.
Kaur D, Arora C, Raghava G
Mol Diagn Ther . 2021 Jun; 25(5):629-646. PMID: 34155607
Introduction: Uterine corpus endometrial carcinoma (UCEC) causes thousands of deaths per year. To improve the overall survival of patients with UCEC, there is a need to identify prognostic biomarkers and...
10.
Sharma N, Patiyal S, Dhall A, Pande A, Arora C, Raghava G
Brief Bioinform . 2020 Nov; 22(4). PMID: 33201237
AlgPred 2.0 is a web server developed for predicting allergenic proteins and allergenic regions in a protein. It is an updated version of AlgPred developed in 2006. The dataset used...