Chaim Linhart
Overview
Explore the profile of Chaim Linhart including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
991
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0
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Recent Articles
1.
Krishnamurthy S, Schnitt S, Vincent-Salomon A, Canas-Marques R, Colon E, Kantekure K, et al.
JCO Precis Oncol
. 2024 Oct;
8:e2400353.
PMID: 39393036
Purpose: The proven efficacy of human epidermal growth factor receptor 2 (HER2) antibody-drug conjugate therapy for treating HER2-low breast cancers necessitates more accurate and reproducible HER2 immunohistochemistry (IHC) scoring. We...
2.
Lami K, Yoon H, Parwani A, Pham H, Tachibana Y, Linhart C, et al.
Pathology
. 2024 May;
56(5):633-642.
PMID: 38719771
Prostate and breast cancer incidence rates have been on the rise in Japan, emphasising the need for precise histopathological diagnosis to determine patient prognosis and guide treatment decisions. However, existing...
3.
Sandbank J, Bataillon G, Nudelman A, Krasnitsky I, Mikulinsky R, Bien L, et al.
NPJ Breast Cancer
. 2022 Dec;
8(1):129.
PMID: 36473870
Breast cancer is the most common malignant disease worldwide, with over 2.26 million new cases in 2020. Its diagnosis is determined by a histological review of breast biopsy specimens, which...
4.
Pantanowitz L, Quiroga-Garza G, Bien L, Heled R, Laifenfeld D, Linhart C, et al.
Lancet Digit Health
. 2020 Dec;
2(8):e407-e416.
PMID: 33328045
Background: There is high demand to develop computer-assisted diagnostic tools to evaluate prostate core needle biopsies (CNBs), but little clinical validation and a lack of clinical deployment of such tools....
5.
Hait T, Maron-Katz A, Sagir D, Amar D, Ulitsky I, Linhart C, et al.
J Mol Biol
. 2019 May;
431(13):2398-2406.
PMID: 31100387
Genome-wide analysis of cellular transcriptomes using RNA-seq or expression arrays is a major mainstay of current biological and biomedical research. EXPANDER (EXPression ANalyzer and DisplayER) is a comprehensive software package...
6.
Orenstein Y, Linhart C, Shamir R
PLoS One
. 2012 Oct;
7(9):e46145.
PMID: 23029415
The new technology of protein binding microarrays (PBMs) allows simultaneous measurement of the binding intensities of a transcription factor to tens of thousands of synthetic double-stranded DNA probes, covering all...
7.
Linhart C, Halperin Y, Darom A, Kidron S, Broday L, Shamir R
Genome Res
. 2011 Sep;
22(1):76-83.
PMID: 21930893
In this study we report on a novel pair of cis-regulatory motifs in promoter sequences of the nematode Caenorhabditis elegans. The motif pair exhibits extraordinary genomic traits: The order and...
8.
Rashi-Elkeles S, Elkon R, Shavit S, Lerenthal Y, Linhart C, Kupershtein A, et al.
Mol Oncol
. 2011 Jul;
5(4):336-48.
PMID: 21795128
The cellular response to DNA damage is vital for maintaining genomic stability and preventing undue cell death or cancer formation. The DNA damage response (DDR), most robustly mobilized by double-strand...
9.
Ozery-Flato M, Linhart C, Trakhtenbrot L, Izraeli S, Shamir R
Genome Biol
. 2011 Jul;
12(6):R61.
PMID: 21714908
Background: Chromosomal aneuploidy, that is to say the gain or loss of chromosomes, is the most common abnormality in cancer. While certain aberrations, most commonly translocations, are known to be...
10.
Ulitsky I, Maron-Katz A, Shavit S, Sagir D, Linhart C, Elkon R, et al.
Nat Protoc
. 2010 Feb;
5(2):303-22.
PMID: 20134430
A major challenge in the analysis of gene expression microarray data is to extract meaningful biological knowledge out of the huge volume of raw data. Expander (EXPression ANalyzer and DisplayER)...