Chad Torrice
Overview
Explore the profile of Chad Torrice including associated specialties, affiliations and a list of published articles.
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17
Citations
2713
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Recent Articles
1.
Zimmerman S, Procasky S, Smith S, Liu J, Torrice C, Souroullas G
bioRxiv
. 2024 Nov;
PMID: 39605688
Mutations in the histone methyltransferase EZH2, particularly the Y641 hotspot mutation, have been implicated in hematologic malignancies, yet the effect of timing and cellular context on their oncogenic potential has...
2.
Pustavoitau A, Barodka V, Sharpless N, Torrice C, Nyhan D, Berkowitz D, et al.
Exp Gerontol
. 2021 Jan;
144:111217.
PMID: 33402297
No abstract available.
3.
Maas B, Francis O, Mollan K, Lee C, Cottrell M, Prince H, et al.
PLoS One
. 2016 Dec;
11(12):e0168709.
PMID: 28036343
Objectives: As the HIV-infected population ages, the role of cellular senescence and inflammation on co-morbid conditions and pharmacotherapy is increasingly of interest. p16INK4a expression, a marker for aging and senescence...
4.
Wood W, Krishnamurthy J, Mitin N, Torrice C, Parker J, Snavely A, et al.
EBioMedicine
. 2016 Sep;
11:227-238.
PMID: 27591832
The expression of markers of cellular senescence increases exponentially in multiple tissues with aging. Age-related physiological changes may contribute to adverse outcomes in cancer survivors. To investigate the impact of...
5.
Dumond J, Francis O, Cottrell M, Trezza C, Prince H, Mollan K, et al.
Antivir Ther
. 2016 Jan;
21(5):441-5.
PMID: 26731175
Background: HIV may amplify immunological, physiological and functional changes of ageing. We determined associations of frailty phenotype, a T-cell senescence marker (p16(INK4a) expression), age and demographics with exposures of the...
6.
Pustavoitau A, Barodka V, Sharpless N, Torrice C, Nyhan D, Berkowitz D, et al.
Exp Gerontol
. 2015 Dec;
74:29-36.
PMID: 26692418
Adults older than 65 years undergo more than 120,000 coronary artery bypass (CAB) procedures each year in the United States. Chronological age alone, though commonly used in prediction models of...
7.
Sanoff H, Deal A, Krishnamurthy J, Torrice C, Dillon P, Sorrentino J, et al.
J Natl Cancer Inst
. 2014 Apr;
106(4):dju057.
PMID: 24681605
Background: Senescent cells, which express p16 (INK4a) , accumulate with aging and contribute to age-related pathology. To understand whether cytotoxic agents promote molecular aging, we measured expression of p16 (INK4a)...
8.
Rozenberg G, Monahan K, Torrice C, Bear J, Sharpless N
Melanoma Res
. 2010 Aug;
20(5):361-71.
PMID: 20679910
Melanoma is the most lethal skin tumor in large part because of a propensity for early metastasis. Good models of this most clinically relevant feature of melanoma are lacking. Here,...
9.
Song Z, von Figura G, Liu Y, Kraus J, Torrice C, Dillon P, et al.
Aging Cell
. 2010 Jun;
9(4):607-15.
PMID: 20560902
Cellular aging is characterized by telomere shortening, which can lead to uncapping of chromosome ends (telomere dysfunction) and activation of DNA damage responses. There is some evidence that DNA damage...
10.
Liu Y, Sanoff H, Cho H, Burd C, Torrice C, Ibrahim J, et al.
Aging Cell
. 2009 Jun;
8(4):439-48.
PMID: 19485966
Expression of the p16(INK4a) tumor suppressor sharply increases with age in most mammalian tissues, and contributes to an age-induced functional decline of certain self-renewing compartments. These observations have suggested that...