Cesar Nombela
Overview
Explore the profile of Cesar Nombela including associated specialties, affiliations and a list of published articles.
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94
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2675
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Recent Articles
11.
Garcia R, Sanz A, Rodriguez-Pena J, Nombela C, Arroyo J
J Cell Sci
. 2016 Mar;
129(8):1649-60.
PMID: 26933180
Activation of the yeast cell wall integrity (CWI) pathway induces an adaptive transcriptional programme that is largely dependent on the transcription factor Rlm1 and the mitogen-activated protein kinase (MAPK) Slt2....
12.
Pitarch A, Nombela C, Gil C
Data Brief
. 2016 Feb;
6:257-61.
PMID: 26862568
The characterization of pathogen-specific antigenic proteins at the protein species level is crucial in the development and molecular optimization of novel immunodiagnostics, vaccines or immunotherapeutics for infectious diseases. The major...
13.
Marin E, Parra-Giraldo C, Hernandez-Haro C, Hernaez M, Nombela C, Monteoliva L, et al.
Front Microbiol
. 2015 Dec;
6:1343.
PMID: 26696967
Candida albicans is a human opportunistic fungus and it is responsible for a wide variety of infections, either superficial or systemic. C. albicans is a polymorphic fungus and its ability...
14.
Pitarch A, Nombela C, Gil C
J Proteomics
. 2015 Oct;
134:144-162.
PMID: 26485298
Serum antibodies to specific Candida proteins have been reported as potential diagnostic biomarkers for candidemia. However, their diagnostic usefulness at the protein species level has hardly been examined. Using serological...
15.
Garcia R, Botet J, Rodriguez-Pena J, Bermejo C, Ribas J, Revuelta J, et al.
BMC Genomics
. 2015 Sep;
16:683.
PMID: 26341223
Background: The fungal cell wall forms a compact network whose integrity is essential for cell morphology and viability. Thus, fungal cells have evolved mechanisms to elicit adequate adaptive responses when...
16.
Blanco N, Sanz A, Rodriguez-Pena J, Nombela C, Farkas V, Hurtado-Guerrero R, et al.
FEBS J
. 2014 Dec;
282(4):715-31.
PMID: 25495733
Covalent cross-links between chitin and glucan at the yeast cell wall are created by the transglycosylase activity of redundant proteins Crh1 and Crh2, with cleavage of β-1,4 linkages of the...
17.
Pitarch A, Nombela C, Gil C
J Proteome Res
. 2014 Nov;
13(11):5165-84.
PMID: 25377742
Invasive candidiasis (IC) adds significantly to the morbidity and mortality of non-neutropenic patients if not diagnosed and treated early. To uncover serologic biomarkers that alone or in combination could reliably...
18.
Gil-Bona A, Llama-Palacios A, Parra C, Vivanco F, Nombela C, Monteoliva L, et al.
J Proteome Res
. 2014 Nov;
14(1):142-53.
PMID: 25367658
The commensal fungus Candida albicans secretes a considerable number of proteins and, as in different fungal pathogens, extracellular vesicles (EVs) have also been observed. Our report contains the first proteomic...
19.
Rodriguez-Pena J, Diez-Muniz S, Bermejo C, Nombela C, Arroyo J
FEBS Lett
. 2013 Oct;
587(22):3675-80.
PMID: 24100139
Yeast adaptation to conditions in which cell wall integrity is compromised mainly relies on the cell wall integrity (CWI) mitogen-activated protein kinase (MAPK) pathway. Zymolyase, a mixture of cell wall-digesting...
20.
Reales-Calderon J, Sylvester M, Strijbis K, Jensen O, Nombela C, Molero G, et al.
J Proteomics
. 2013 Jul;
91:106-35.
PMID: 23832136
Biological Significance: This work uses SILAC and SIMAC methodology combined with CPP (+ TiO2) to study protein and phosphopeptide changes in RAW 264.7 macrophages in response to coincubation with Candida...