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Cenglin Xu

Explore the profile of Cenglin Xu including associated specialties, affiliations and a list of published articles. Areas
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Articles 68
Citations 758
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Recent Articles
1.
Tan B, Wu X, Ding Y, Yuan C, Jin Y, Xu C, et al.
Commun Biol . 2025 Mar; 8(1):416. PMID: 40069548
Neuropathic pain involves complex cortical mechanisms, yet the role of the medial secondary visual cortex (V2M) remains poorly understood. We hypothesized that glutamatergic neurons in V2M (V2M) contribute to pain...
2.
Zhang S, Xu L, Ding Y, Xu C
Neurosci Bull . 2025 Mar; PMID: 40025260
No abstract available.
3.
Zou S, Gong Y, Yan M, Yuan Z, Sun M, Zhang S, et al.
CNS Neurosci Ther . 2025 Feb; 31(2):e70265. PMID: 39924980
Aims: The limited efficacy and very restricted antiseizure range of current deep brain stimulation (DBS) targets highlight the need to find an optimal target for managing various seizure types. Here,...
4.
He C, Hu W, Xiong K, Ye L, Ye H, Hu L, et al.
Clin Neurophysiol . 2025 Feb; 171:124-132. PMID: 39904142
Objectives: We investigated EEG features differentiating clinical seizures (CSs) from subclinical seizures (SCSs) to explore the mechanisms underlying the generation of ictal behavior in mesial temporal lobe epilepsy (mTLE). Methods:...
5.
Gong Y, Zhang Z, Yang Y, Zhang S, Zheng R, Li X, et al.
Neurosci Bull . 2025 Jan; PMID: 39869168
Approximately 30%-40% of epilepsy patients do not respond well to adequate anti-seizure medications (ASMs), a condition known as pharmacoresistant epilepsy. The management of pharmacoresistant epilepsy remains an intractable issue in...
6.
Fei F, Wang X, Fan X, Gong Y, Yang L, Wang Y, et al.
J Neurosci . 2024 Dec; 45(5). PMID: 39658255
The subiculum represents a crucial brain pivot in regulating seizure generalization in temporal lobe epilepsy (TLE), primarily through a synergy of local GABAergic and long-projecting glutamatergic signaling. However, little is...
7.
Li Z, Chen L, Fei F, Wang W, Yang L, Wang Y, et al.
Adv Sci (Weinh) . 2024 Oct; 11(46):e2410927. PMID: 39435757
Enriched environment (EE), characterized by multi-sensory stimulation, represents a non-invasive alternative for alleviating epileptic seizures. However, the mechanism by which EE exerts its therapeutic impact remains incompletely understood. Here, it...
8.
Gao S, Gong Y, Xu C, Chen Z
Epilepsia Open . 2024 Oct; 9(6):2112-2127. PMID: 39403878
Epilepsy is a prevalent neurological disease that impacts around 70 million individuals globally. Anti-seizure medications (ASMs) are the first choice for clinicians to control unprovoked epileptic seizures. Although more than...
9.
Zhang X, Xu C, Chen Z
Neurosci Bull . 2024 Aug; 41(1):186-188. PMID: 39177887
No abstract available.
10.
Tang Y, Liu Y, Gong Y, Zhang S, Cui S, Wang Y, et al.
Neurochem Int . 2024 Jul; 179:105809. PMID: 39047793
Current anti-seizure medications (ASDs) primarily target ion channels or neurotransmissions; however, their practicability is limited by unwanted side-effects and pharmacoresistance. Cumulative evidence has proposed pro-inflammatory caspase-1 as a potential target...