Celina Whalley
Overview
Explore the profile of Celina Whalley including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
369
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0
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Recent Articles
1.
Schoenpflug L, Chatzipli A, Sirinukunwattana K, Richman S, Blake A, Robineau J, et al.
J Pathol
. 2024 Dec;
265(2):184-197.
PMID: 39710952
Tumour content plays a pivotal role in directing the bioinformatic analysis of molecular profiles such as copy number variation (CNV). In clinical application, tumour purity estimation (TPE) is achieved either...
2.
Wismayer R, Matthews R, Whalley C, Kiwanuka J, Kakembo F, Thorn S, et al.
BMC Cancer
. 2024 Sep;
24(1):1212.
PMID: 39350061
Uganda is a developing low-income country with a low incidence of colorectal cancer, which is steadily increasing. Ugandan colorectal cancer (CRC) patients are young and present with advanced-stage disease. In...
3.
Hadzhiev Y, Wheatley L, Cooper L, Ansaloni F, Whalley C, Chen Z, et al.
Dev Cell
. 2023 Jan;
58(2):155-170.e8.
PMID: 36693321
In anamniote embryos, the major wave of zygotic genome activation starts during the mid-blastula transition. However, some genes escape global genome repression, are activated substantially earlier, and contribute to the...
4.
Panetti S, McJannett N, Fultang L, Booth S, Gneo L, Scarpa U, et al.
Blood Adv
. 2022 Dec;
7(9):1754-1761.
PMID: 36521029
Cancer cells take up amino acids from the extracellular space to drive cell proliferation and viability. Similar mechanisms are applied by immune cells, resulting in the competition between conventional T...
5.
Palles C, West H, Chew E, Galavotti S, Flensburg C, Grolleman J, et al.
Am J Hum Genet
. 2022 Apr;
109(5):953-960.
PMID: 35460607
We report an autosomal recessive, multi-organ tumor predisposition syndrome, caused by bi-allelic loss-of-function germline variants in the base excision repair (BER) gene MBD4. We identified five individuals with bi-allelic MBD4...
6.
Kidd S, Burns D, Armson B, Beggs A, Howson E, Williams A, et al.
J Mol Diagn
. 2022 Feb;
24(4):320-336.
PMID: 35121140
Previous studies have described reverse-transcription loop-mediated isothermal amplification (RT-LAMP) for the rapid detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in nasopharyngeal/oropharyngeal swab and saliva samples. This multisite clinical...
7.
Manzoor S, Zaman S, Whalley C, Inglis D, Bosworth A, Kidd M, et al.
F1000Res
. 2021 Aug;
10:373.
PMID: 34367617
Faecal transplantation is an evidence-based treatment for . Patients infected with SARS-CoV-2 have been shown to shed the virus in stool for up to 33 days, well beyond the average...
8.
Stockton J, Tee L, Whalley C, James J, Dilworth M, Wheat R, et al.
Radiat Oncol
. 2021 Jul;
16(1):129.
PMID: 34256782
Background: Pathological complete response (pathCR) in rectal cancer is beneficial, as up to 75% of patients do not experience regrowth of the primary tumour, but it is poorly understood. We...
9.
Ptasinska A, Whalley C, Bosworth A, Poxon C, Bryer C, Machin N, et al.
Clin Microbiol Infect
. 2021 Apr;
27(9):1348.e1-1348.e7.
PMID: 33901668
Objectives: Rapid, high throughput diagnostics are a valuable tool, allowing the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in populations so as to identify and isolate people with...
10.
Whalley C, Payne K, Domingo E, Blake A, Richman S, Brooks J, et al.
Epigenomes
. 2021 Mar;
5(1):6.
PMID: 33777442
Methods: For all experiments, the Infinium HD assay for methylation was used. In total, forty-eight FFPE specimens were used at varying concentrations (lowest input 50 ng); eighteen blood derived specimens...