Celeste B Greer
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Explore the profile of Celeste B Greer including associated specialties, affiliations and a list of published articles.
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11
Citations
298
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Recent Articles
1.
Htet M, Estay-Olmos C, Hu L, Wu Y, Powers B, Campbell C, et al.
bioRxiv
. 2024 Oct;
PMID: 39386727
Graphical Abstract:
2.
Haynes J, Whitmore C, Behof W, Landman C, Ong H, Feld A, et al.
Sci Rep
. 2024 Jul;
14(1):16086.
PMID: 38992064
The classical amyloid cascade hypothesis postulates that the aggregation of amyloid plaques and the accumulation of intracellular hyperphosphorylated Tau tangles, together, lead to profound neuronal death. However, emerging research has...
3.
Haynes J, Whitmore C, Behof W, Landman C, Ong H, Feld A, et al.
Res Sq
. 2024 Apr;
PMID: 38559050
The classical amyloid cascade hypothesis postulates that the aggregation of amyloid plaques and the accumulation of intracellular hyperphosphorylated Tau tangles, together, lead to profound neuronal death. However, emerging research has...
4.
Stefanelli G, Makowski C, Brimble M, Hall M, Reda A, Creighton S, et al.
Cell Rep
. 2021 Aug;
36(7):109551.
PMID: 34407406
Rapid removal of histone H2A.Z from neuronal chromatin is a key step in learning-induced gene expression and memory formation, but mechanisms underlying learning-induced H2A.Z removal are unclear. Anp32e was recently...
5.
Poplawski S, Garbett K, McMahan R, Kordasiewicz H, Zhao H, Kennedy A, et al.
Mol Ther Nucleic Acids
. 2020 Mar;
19:1399-1412.
PMID: 32160709
Knockout of the memory suppressor gene histone deacetylase 2 (Hdac2) in mice elicits cognitive enhancement, and drugs that block HDAC2 have potential as therapeutics for disorders affecting memory. Currently available...
6.
Cai W, Greer C, Chen J, Arnal-Estape A, Cao J, Yan Q, et al.
BMC Med Genomics
. 2020 Mar;
13(1):33.
PMID: 32143622
Background: Few somatic mutations have been linked to breast cancer metastasis, whereas transcriptomic differences among primary tumors correlate with incidence of metastasis, especially to the lungs and brain. However, the...
7.
Collins B, Sweatt J, Greer C
Neurobiol Learn Mem
. 2019 Apr;
161:149-157.
PMID: 31002880
Transcriptional changes in the hippocampus are required for memory formation, and these changes are regulated by numerous post-translational modifications of chromatin-associated proteins. One of the epigenetic marks that has been...
8.
Collins B, Greer C, Coleman B, Sweatt J
Epigenetics Chromatin
. 2019 Jan;
12(1):7.
PMID: 30616667
Epigenetic modifications such as histone methylation permit change in chromatin structure without accompanying change in the underlying genomic sequence. A number of studies in animal models have shown that dysregulation...
9.
Liao L, Alicea-Velazquez N, Langbein L, Niu X, Cai W, Cho E, et al.
Mol Oncol
. 2018 Dec;
13(4):811-828.
PMID: 30585695
Polybromo-1 (PBRM1) is an important tumor suppressor in kidney cancer. It contains six tandem bromodomains (BDs), which are specialized structures that recognize acetyl-lysine residues. While BD2 has been found to...
10.
Stress from Nucleotide Depletion Activates the Transcriptional Regulator HEXIM1 to Suppress Melanoma
Tan J, Fogley R, Flynn R, Ablain J, Yang S, Saint-Andre V, et al.
Mol Cell
. 2016 Apr;
62(1):34-46.
PMID: 27058786
Studying cancer metabolism gives insight into tumorigenic survival mechanisms and susceptibilities. In melanoma, we identify HEXIM1, a transcription elongation regulator, as a melanoma tumor suppressor that responds to nucleotide stress....