Cedric Cleyrat
Overview
Explore the profile of Cedric Cleyrat including associated specialties, affiliations and a list of published articles.
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Articles
15
Citations
3307
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0
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Recent Articles
1.
Kanagy W, Cleyrat C, Fazel M, Lucero S, Bruchez M, Lidke K, et al.
Mol Biol Cell
. 2022 Jul;
33(10):ar89.
PMID: 35793126
The high-affinity immunoglobulin E (IgE) receptor, FcεRI, is the primary immune receptor found on mast cells and basophils. Signal initiation is classically attributed to phosphorylation of FcεRI β- and γ-subunits...
2.
Allain-Maillet S, Bosseboeuf A, Mennesson N, Bostoen M, Dufeu L, Choi E, et al.
Cancers (Basel)
. 2020 Sep;
12(9).
PMID: 32872203
Inflammatory cytokines play a major role in myeloproliferative neoplasms (MPNs) as regulators of the MPN clone and as mediators of clinical symptoms and complications. Firstly, we investigated the effect of...
3.
Travers T, Kanagy W, Mansbach R, Jhamba E, Cleyrat C, Goldstein B, et al.
Mol Biol Cell
. 2019 Jun;
30(17):2331-2347.
PMID: 31216232
Syk/Zap70 family kinases are essential for signaling via multichain immune-recognition receptors such as tetrameric (αβγ2) FcεRI. Syk activation is generally attributed to binding of its tandem SH2 domains to dual...
4.
Cleyrat C, Girard R, Choi E, Jeziorski E, Lavabre-Bertrand T, Hermouet S, et al.
Blood Adv
. 2018 Jan;
1(21):1815-1826.
PMID: 29296828
Thrombopoietin (Tpo) and its receptor (Mpl) are the principal regulators of early and late thrombopoiesis and hematopoietic stem cell maintenance. Mutations in can drastically impair its function and be a...
5.
Schwartz S, Cleyrat C, Olah M, Relich P, Phillips G, Hlavacek W, et al.
Mol Biol Cell
. 2017 Sep;
28(23):3397-3414.
PMID: 28855374
Cross-linking of immunoglobulin E-bound FcεRI triggers multiple cellular responses, including degranulation and cytokine production. Signaling is dependent on recruitment of Syk via docking of its dual SH2 domains to phosphorylated...
6.
Mahajan A, Youssef L, Cleyrat C, Grattan R, Lucero S, Mattison C, et al.
J Immunol
. 2017 Jan;
198(3):1034-1046.
PMID: 28039304
Ag-mediated crosslinking of IgE-FcεRI complexes activates mast cells and basophils, initiating the allergic response. Of 34 donors recruited having self-reported shrimp allergy, only 35% had significant levels of shrimp-specific IgE...
7.
Klionsky D, Abdelmohsen K, Abe A, Abedin M, Abeliovich H, Arozena A, et al.
Autophagy
. 2016 Jan;
12(1):1-222.
PMID: 26799652
No abstract available.
8.
Ponpuak M, Mandell M, Kimura T, Chauhan S, Cleyrat C, Deretic V
Curr Opin Cell Biol
. 2015 May;
35:106-16.
PMID: 25988755
Autophagy, once viewed exclusively as a cytoplasmic auto-digestive process, has its less intuitive but biologically distinct non-degradative roles. One manifestation of these functions of the autophagic machinery is the process...
9.
DeVore M, Stich D, Keller A, Ghosh Y, Goodwin P, Phipps M, et al.
Proc SPIE Int Soc Opt Eng
. 2015 May;
9338.
PMID: 25932286
Single particle tracking has provided a wealth of information about biophysical processes such as motor protein transport and diffusion in cell membranes. However, motion out of the plane of the...
10.
Cleyrat C, Darehshouri A, Steinkamp M, Vilaine M, Boassa D, Ellisman M, et al.
Traffic
. 2014 Jun;
15(9):961-82.
PMID: 24931576
Myeloproliferative neoplasms (MPNs) are often characterized by JAK2 or calreticulin (CALR) mutations, indicating aberrant trafficking in pathogenesis. This study focuses on Mpl trafficking and Jak2 association using two model systems:...