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» Authors » Cecilia Cialdai

Cecilia Cialdai

Explore the profile of Cecilia Cialdai including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 10
Citations 79
Followers 0
Related Specialties
Pharmacology
General Medicine
Science
Top 10 Co-Authors
Claudio Valenti
Carlo Alberto Maggi
Sandro Giuliani
Manuela Tramontana
Stefania Meini
Laura Quartara
Rose-Marie Catalioto
Alessandro Lecci
Claudio Catalani
Maria Altamura
Published In
Eur J Pharmacol
J Pharmacol Exp Ther
Naunyn Schmiedebergs Arch Pharmacol
Br J Pharmacol
PLoS One
Affiliations
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Recent Articles
1.
Booster immunization with a fractional dose of Prevnar 13 affects cell-mediated immune response but not humoral immunity in CD-1 mice
Catalioto R, Valenti C, Bellucci F, Cialdai C, Altamura M, Digilio L, et al.
Heliyon . 2021 Jul; 7(6):e07314. PMID: 34195422
Achieving durable protective immunity following vaccination is dependent on many factors, including vaccine composition and antigen dose, and it has been investigated for various types of vaccines. Aim of the...
2.
Antagonism of bradykinin B2 receptor prevents inflammatory responses in human endothelial cells by quenching the NF-kB pathway activation
Terzuoli E, Meini S, Cucchi P, Catalani C, Cialdai C, Maggi C, et al.
PLoS One . 2014 Jan; 9(1):e84358. PMID: 24392129
Background: Bradykinin (BK) induces angiogenesis by promoting vessel permeability, growth and remodeling. This study aimed to demonstrate that the B2R antagonist, fasitibant, inhibits the BK pro-angiogenic effects. Methodology: We assesed...
3.
Comparison between oral and intra-articular antinociceptive effect of dexketoprofen and tramadol combination in monosodium iodoacetate-induced osteoarthritis in rats
Cialdai C, Giuliani S, Valenti C, Tramontana M, Maggi C
Eur J Pharmacol . 2013 Jul; 714(1-3):346-51. PMID: 23891968
Dexketoprofen and tramadol, alone or in combination, were evaluated after oral or intra-articular administration on knee osteoarthritis nociception induced by intra-articular (i.ar.) monosodium iodoacetate (MIA, 1 mg/25 µl) in the...
4.
Fasitibant chloride, a kinin B₂ receptor antagonist, and dexamethasone interact to inhibit carrageenan-induced inflammatory arthritis in rats
Valenti C, Giuliani S, Cialdai C, Tramontana M, Maggi C
Br J Pharmacol . 2012 Jan; 166(4):1403-10. PMID: 22251015
Background And Purpose: Bradykinin, through the kinin B₂ receptor, is involved in inflammatory processes related to arthropathies. B₂ receptor antagonists inhibited carrageenan-induced arthritis in rats in synergy with anti-inflammatory steroids....
5.
Differences between zofenopril and ramipril, two ACE inhibitors, on cough induced by citric acid in guinea pigs: role of bradykinin and PGE2
Cialdai C, Giuliani S, Valenti C, Tramontana M, Maggi C
Naunyn Schmiedebergs Arch Pharmacol . 2010 Sep; 382(5-6):455-61. PMID: 20848272
Dry and persistent cough is one of the commonest side effects experienced by patients treated with angiotensin-converting enzyme (ACE) inhibitors for the therapy of hypertension and congestive heart failure. The...
6.
Effect of Intra-articular 4-(S)-amino-5-(4-{4-[2,4-dichloro-3-(2,4-dimethyl-8-quinolyloxymethyl)phenylsulfonamido]-tetrahydro-2H-4-pyranylcarbonyl} piperazino)-5-oxopentyl](trimethyl)ammonium chloride hydrochloride (MEN16132), a kinin B2 receptor...
Cialdai C, Giuliani S, Valenti C, Tramontana M, Maggi C
J Pharmacol Exp Ther . 2009 Sep; 331(3):1025-32. PMID: 19745108
The present study was designed to investigate the role of bradykinin (BK) in the knee joint osteoarthritis induced by intra-articular (i.ar.) administration of monosodium iodoacetate (MIA) in the rat, and...
7.
Excitatory and inhibitory urinary bladder reflexes induced by stimulation of cervicovaginal capsaicin-sensitive sensory fibers in rats
Tramontana M, Giuliani S, Valenti C, Cialdai C, Lazzeri M, Turini D, et al.
Naunyn Schmiedebergs Arch Pharmacol . 2008 Oct; 379(2):107-14. PMID: 18839149
We have investigated the effect of intravaginal application of capsaicin on micturition reflex in female rats. Urinary bladder contractility was measured by transurethral pressure recording at isovolumetric and subthreshold conditions...
8.
MEN16132, a kinin B2 receptor antagonist, prevents the endogenous bradykinin effects in guinea-pig airways
Valenti C, Cialdai C, Giuliani S, Tramontana M, Quartara L, Maggi C
Eur J Pharmacol . 2007 Nov; 579(1-3):350-6. PMID: 18036587
Kinins have been suggested to be involved in human airway diseases such as asthma and rhinitis. MEN16132 is a non-peptide kinin B(2) receptor antagonist able to inhibit the responses produced...
9.
MEN15596, a novel nonpeptide tachykinin NK2 receptor antagonist
Cialdai C, Tramontana M, Patacchini R, Lecci A, Catalani C, Catalioto R, et al.
Eur J Pharmacol . 2006 Sep; 549(1-3):140-8. PMID: 16979621
The pharmacological profile of MEN15596 or (6-methyl-benzo[b]thiophene-2-carboxylic acid [1-(2-phenyl-1R-{[1-(tetrahydropyran-4-ylmethyl)-piperidin-4-ylmethyl]-carbamoyl}-ethylcarbamoyl)-cyclopentyl]-amide), a novel potent and selective tachykinin NK2 receptor antagonist endowed with oral activity, is described. At the human recombinant tachykinin NK2...
10.
MEN16132, a novel potent and selective nonpeptide kinin B2 receptor antagonist: in vivo activity on bradykinin-induced bronchoconstriction and nasal mucosa microvascular leakage in anesthetized guinea pigs
Valenti C, Cialdai C, Giuliani S, Lecci A, Tramontana M, Meini S, et al.
J Pharmacol Exp Ther . 2005 Jul; 315(2):616-23. PMID: 16027229
We have tested the activity of 4-(S)-amino-5-(4-[4-[2,4-dichloro-3-(2,4-dimethyl-8-quinolyloxymethyl)phenylsulfonamido]-tetrahydro-2H-4-pyranylcarbonyl] piperazino)-5-oxopentyl](trimethyl)ammonium chloride hydrochloride (MEN16132), a novel nonpeptide kinin B(2) receptor antagonist, on bradykinin (BK)-induced inflammatory responses, bronchoconstriction, and hypotension in guinea pigs. After...