Cecile Pierre-Eugene
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Explore the profile of Cecile Pierre-Eugene including associated specialties, affiliations and a list of published articles.
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22
Citations
602
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Recent Articles
1.
Thirant C, Peltier A, Durand S, Kramdi A, Louis-Brennetot C, Pierre-Eugene C, et al.
Nat Commun
. 2023 May;
14(1):2575.
PMID: 37142597
Noradrenergic and mesenchymal identities have been characterized in neuroblastoma cell lines according to their epigenetic landscapes and core regulatory circuitries. However, their relationship and relative contribution in patient tumors remain...
2.
Tucker E, Jimenez I, Chen L, Bellini A, Gorrini C, Calton E, et al.
Clin Cancer Res
. 2023 Jan;
29(7):1317-1331.
PMID: 36602782
Purpose: ALK-activating mutations are identified in approximately 10% of newly diagnosed neuroblastomas and ALK amplifications in a further 1%-2% of cases. Lorlatinib, a third-generation anaplastic lymphoma kinase (ALK) inhibitor, will...
3.
Costa A, Thirant C, Kramdi A, Pierre-Eugene C, Louis-Brennetot C, Blanchard O, et al.
J Immunother Cancer
. 2022 Sep;
10(8).
PMID: 36054452
Background: High-risk neuroblastoma is a pediatric cancer with still a dismal prognosis, despite multimodal and intensive therapies. Tumor microenvironment represents a key component of the tumor ecosystem the complexity of...
4.
Sriha J, Louis-Brennetot C, Pierre-Eugene C, Baulande S, Raynal V, Kramdi A, et al.
Cancers (Basel)
. 2022 Jun;
14(11).
PMID: 35681734
Neuroblastoma arising from the adrenal differ from ganglionic neuroblastoma both genetically and clinically, with adrenal tumors being associated with a more severe prognosis. The different tumor properties may be linked...
5.
Sole A, Grossetete S, Heintze M, Babin L, Zaidi S, Revy P, et al.
Cancer Res
. 2021 Aug;
81(19):4994-5006.
PMID: 34341072
Ewing sarcoma is characterized by pathognomonic translocations, most frequently fusing with . An estimated 30% of Ewing sarcoma tumors also display genetic alterations in , , or (). Numerous attempts...
6.
Durand S, Pierre-Eugene C, Mirabeau O, Louis-Brennetot C, Combaret V, Colmet-Daage L, et al.
Oncotarget
. 2019 Aug;
10(48):4937-4950.
PMID: 31452835
The gene is a major oncogene of neuroblastoma cases exhibiting ALK activating mutations. Here, we characterized two neuroblastoma cell lines established from a stage 4 patient at diagnosis either from...
7.
Lopez-Delisle L, Pierre-Eugene C, Louis-Brennetot C, Surdez D, Raynal V, Baulande S, et al.
Oncogene
. 2018 Jan;
37(11):1417-1429.
PMID: 29321660
Activating mutations of the ALK receptor occur in a subset of neuroblastoma tumors. We previously demonstrated that Alk mutations cooperate with MYCN overexpression to induce neuroblastoma in mice and identified...
8.
Gondoin A, Hampe C, Eudes R, Fayolle C, Pierre-Eugene C, Miteva M, et al.
Sci Rep
. 2017 Dec;
7(1):16901.
PMID: 29203791
Metabolic diseases are characterized by a decreased action of insulin. During the course of the disease, usual treatments frequently fail and patients are finally submitted to insulinotherapy. There is thus...
9.
Boeva V, Louis-Brennetot C, Peltier A, Durand S, Pierre-Eugene C, Raynal V, et al.
Nat Genet
. 2017 Jul;
49(9):1408-1413.
PMID: 28740262
Neuroblastoma is a tumor of the peripheral sympathetic nervous system, derived from multipotent neural crest cells (NCCs). To define core regulatory circuitries (CRCs) controlling the gene expression program of neuroblastoma,...
10.
Raimbault A, Pierre-Eugene C, Rouquette A, Deudon C, Willems L, Chapuis N, et al.
Oncotarget
. 2016 Feb;
7(12):14898-911.
PMID: 26910909
CD95, a member of the death receptor family initiates a caspase-dependent apoptosis, when activated by its ligand CD95L, thought to negatively regulate erythrocyte production in the bone marrow. We have...