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Cecile Michel

Explore the profile of Cecile Michel including associated specialties, affiliations and a list of published articles. Areas
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Articles 31
Citations 201
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Recent Articles
21.
Wilks M, Blaauboer B, Schulte-Hermann R, Wallace H, Galli C, Haag-Gronlund M, et al.
Toxicol Lett . 2016 Jun; 259:151-155. PMID: 27343956
Following its inception in 1994, the certification of European Registered Toxicologists (ERT) by EUROTOX has been recognized as ensuring professional competence as well as scientific integrity and credibility. Criteria and...
22.
Michel C, Vincent-Hubert F
Ecotoxicology . 2015 Oct; 24(9):2009-16. PMID: 26438356
Freshwater bivalve molluscs are considered as effective indicators of environmental pollution. The comet assay allows the detection of DNA damage such as DNA strand breaks and alkali-labile sites. The main...
23.
Marcy P, Dahlet C, Brenet O, Yazbec G, Dubois P, Salm B, et al.
Bull Cancer . 2015 Mar; 102(4):301-15. PMID: 25799876
Objective: Most cancer patients require a totally-implanted central venous access device (TIVAD) for their treatment. This was a prospective, multicenter, open study to: (i) develop and validate a French-language questionnaire...
24.
Michel C, Bourgeault A, Gourlay-France C, Palais F, Geffard A, Vincent-Hubert F
Ecotoxicol Environ Saf . 2013 Mar; 92:18-26. PMID: 23490194
Genotoxicity endpoints are useful tools to biomonitor the physicochemical and biological quality of aquatic ecosystems. A caging study on the freshwater bivalve Dreissena polymorpha was planned to run over four...
25.
Francois E, Smith D, Dahan L, Michel C, Perrier H, Mari V, et al.
J Chemother . 2012 Oct; 24(4):207-11. PMID: 23040684
We investigated the efficacy and safety of oral Uracil/tegafur (UFT) with leucovorin and mitomycin C (MMC) as third-line treatment for patients with extensively pretreated metastatic colorectal cancer (mCRC). This was...
26.
Michel C, Vincent-Hubert F
Mutat Res . 2011 Oct; 741(1-2):1-6. PMID: 22009068
Genotoxic end-points are routinely measured in various sentinel organisms in aquatic environments in order to monitor the impact of water pollution on organisms. As a first step towards the evaluation...
27.
Engel C, Versmold B, Wappenschmidt B, Simard J, Easton D, Peock S, et al.
Cancer Epidemiol Biomarkers Prev . 2010 Oct; 19(11):2859-68. PMID: 20978178
Background: The genes caspase-8 (CASP8) and caspase-10 (CASP10) functionally cooperate and play a key role in the initiation of apoptosis. Suppression of apoptosis is one of the major mechanisms underlying...
28.
Michel C, Desdouets C, Slaoui M, Isaacs K, Roberts R, Boitier E
Toxicol Sci . 2007 Jul; 99(1):58-69. PMID: 17602206
Clofibric acid (CLO) is a nongenotoxic hepatocarcinogen in rodents that causes altered hepatocellular foci and/or neoplasms. Initiation by DNA-damaging agents such as diethylnitrosamine (DEN) accelerates focus and tumor appearance and...
29.
Michel C, Roberts R, Desdouets C, Isaacs K, Boitier E
Chem Res Toxicol . 2005 Apr; 18(4):611-8. PMID: 15833021
Evaluation of the nongenotoxic potential early during the development of a drug presents a major challenge. Recently, two genes were identified as potential molecular markers of rodent hepatic carcinogenesis: transforming...
30.
Roberts R, Michel C, Coyle B, Freathy C, Cain K, Boitier E
Toxicol Lett . 2004 Apr; 149(1-3):37-41. PMID: 15093246
Peroxisome proliferators (PPs) constitute a large and chemically diverse family of non-genotoxic rodent hepatocarcinogens that activate the PP-activated receptor alpha (PPARalpha). In order to investigate the hypothesis that PPs elicit...