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Catherine M Crosby

Explore the profile of Catherine M Crosby including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 371
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Recent Articles
1.
Murray M, Crosby C, Marcovecchio P, Hartmann N, Chandra S, Zhao M, et al.
Cell Rep . 2022 Jan; 38(2):110209. PMID: 35021099
Innate-like T cells, including invariant natural killer T cells, mucosal-associated invariant T cells, and γδ T cells, are present in various barrier tissues, including the lung, where they carry out...
2.
Chandra S, Gray J, Kiosses W, Khurana A, Hitomi K, Crosby C, et al.
Nat Commun . 2018 Oct; 9(1):4279. PMID: 30323255
Invariant natural killer T cells (iNKT cells) are activated by lipid antigens presented by CD1d, but the pathway leading to lipid antigen presentation remains incompletely characterized. Here we show a...
3.
Crosby C, Kronenberg M
Nat Rev Immunol . 2018 Jul; 18(9):559-574. PMID: 29967365
Invariant natural killer T cells (iNKT cells) are an innate-like T cell subset that expresses an invariant T cell receptor (TCR) α-chain and recognizes lipids presented on CD1d. They secrete...
4.
Nguyen T, Crosby C, Heller G, Mendel Z, Barry M, Barry M
Oncolytic Virother . 2018 May; 7:43-51. PMID: 29765912
Background: Human species C adenovirus serotype 5 (Ad5) is the archetype oncolytic adenovirus and has been used in the vast majority of preclinical and clinical tests. While Ad5 can be...
5.
Nguyen T, Barry M, Turner M, Crosby C, Trujillo M, Morris J, et al.
Biomedicines . 2017 Aug; 5(3). PMID: 28796161
Oncolytic viruses would ideally be of use for systemic therapy to treat disseminated cancer. To do this safely, this may require multiple layers of cancer specificity. The pharmacology and specificity...
6.
Crosby C, Barry M
Genes (Basel) . 2017 Feb; 8(2). PMID: 28218713
Most adenovirus (Ad) vectors are E1 gene deleted replication defective (RD-Ad) vectors that deliver one transgene to the cell and all expression is based on that one gene. In contrast,...
7.
Crosby C, Matchett W, Anguiano-Zarate S, Parks C, Weaver E, Pease L, et al.
J Virol . 2016 Nov; 91(2). PMID: 27807231
Importance: Most adenovirus vaccines that are being tested are replication-defective adenoviruses (RD-Ads). This work describes testing newer single-cycle adenovirus (SC-Ad) vectors that replicate transgenes to amplify protein production and immune...
8.
Crosby C, Kronenberg M
Immunogenetics . 2016 Jul; 68(8):639-48. PMID: 27368411
Invariant natural killer T (iNKT) cells constitute a unique subset of innate-like T cells that have been shown to have crucial roles in a variety of immune responses. iNKT cells...
9.
Nguyen T, Heller G, Barry M, Crosby C, Turner M, Barry M
Mol Ther Oncolytics . 2016 Feb; 3. PMID: 26900598
Oncolytic viruses hold promise as "self-amplifying" cancer therapies wherein a virally killed cell can produce thousands of new viral "drugs" that can kill more cancer cells. Adenoviruses (Ads) are one...
10.
Crosby C, Weaver E, Khare R, Barry M
Virol Rep . 2015 Nov; 5:47-55. PMID: 26550557
Simian immunodeficiency virus (SIV) is a robust pathogen used in non-human primates to model HIV vaccines. SIV encodes a number of potential vaccine targets. By far the largest and most...