Catherine Lee May
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Explore the profile of Catherine Lee May including associated specialties, affiliations and a list of published articles.
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21
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Recent Articles
11.
Schaffer A, Taylor B, Benthuysen J, Liu J, Thorel F, Yuan W, et al.
PLoS Genet
. 2013 Feb;
9(1):e1003274.
PMID: 23382704
All pancreatic endocrine cell types arise from a common endocrine precursor cell population, yet the molecular mechanisms that establish and maintain the unique gene expression programs of each endocrine cell...
12.
Hunter C, Dixit S, Cohen T, Ediger B, Wilcox C, Ferreira M, et al.
Diabetes
. 2012 Nov;
62(3):875-86.
PMID: 23193182
Ldb1 and Ldb2 are coregulators that mediate Lin11-Isl1-Mec3 (LIM)-homeodomain (HD) and LIM-only transcription factor-driven gene regulation. Although both Ldb1 and Ldb2 mRNA were produced in the developing and adult pancreas,...
13.
Liu J, Walp E, May C
Islets
. 2012 May;
4(3):199-206.
PMID: 22595886
A decrease in the expression of Islet-1 (Isl-1), an islet transcription factor, has been reported in several physiological settings of reduced β-cell function. Here, we investigate whether an increased level...
14.
Du A, McCracken K, Walp E, Terry N, Klein T, Han A, et al.
Dev Biol
. 2012 Mar;
365(1):175-88.
PMID: 22387004
Enteroendocrine cells of the gastrointestinal (GI) tract play a central role in metabolism, digestion, satiety and lipid absorption, yet their development remains poorly understood. Here we show that Arx, a...
15.
Mastracci T, Wilcox C, Arnes L, Panea C, Golden J, May C, et al.
Dev Biol
. 2011 Aug;
359(1):1-11.
PMID: 21856296
Nkx2.2 and Arx are essential pancreatic transcription factors. Nkx2.2 is necessary for the appropriate specification of the islet alpha, beta, PP and epsilon cell lineages, whereas Arx is required to...
16.
Liu J, Hunter C, Du A, Ediger B, Walp E, Murray J, et al.
J Biol Chem
. 2011 Mar;
286(17):15352-60.
PMID: 21388963
Aristaless related homeodomain protein (Arx) specifies the formation of the pancreatic islet α-cell during development. This cell type produces glucagon, a major counteracting hormone to insulin in regulating glucose homeostasis...
17.
Das P, May C
Gene Expr Patterns
. 2011 Jan;
11(3-4):244-54.
PMID: 21220053
LIM-homeodomain genes encode a family of proteins defined by the cysteine-rich protein/protein interacting (Lin-11, Isl-1, and Mec-3) LIM domain and a highly conserved DNA-binding domain. Studies in several organisms have...
18.
The role of Islet-1 in the endocrine pancreas: Lessons from pancreas specific Islet-1 deficient mice
May C
Islets
. 2010 Nov;
2(2):121-3.
PMID: 21099304
Recently, we have reported the LIM-homeodoman (HD) transcriptional regulator, Islet-1 (Isl-1) as a key regulator for pancreatic islets after the secondary transition and into early postnatal stages in mice. Previously,...
19.
May C, Kaestner K
Mol Cell Endocrinol
. 2009 Dec;
323(1):70-5.
PMID: 20025933
No abstract available.
20.
Du A, Hunter C, Murray J, Noble D, Cai C, Evans S, et al.
Diabetes
. 2009 Jun;
58(9):2059-69.
PMID: 19502415
Objective: The generation of mature cell types during pancreatic development depends on the expression of many regulatory and signaling proteins. In this study, we tested the hypothesis that the transcriptional...