Catherine J Landis
Overview
Explore the profile of Catherine J Landis including associated specialties, affiliations and a list of published articles.
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5
Citations
161
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Recent Articles
1.
Hawkins C, Jones A, Gordon E, Williford S, Harsh Y, Ziebro J, et al.
Cells
. 2022 Jun;
11(12).
PMID: 35741006
Glioblastoma (GBM) remains one of the most aggressive cancers, partially due to its ability to migrate into the surrounding brain. The sphingolipid balance, or the balance between ceramides and sphingosine-1-phosphate,...
2.
Ghosh J, Perego M, Agarwal E, Bertolini I, Wang Y, Goldman A, et al.
Proc Natl Acad Sci U S A
. 2022 Feb;
119(8).
PMID: 35177476
Cancer metabolism, including in mitochondria, is a disease hallmark and therapeutic target, but its regulation is poorly understood. Here, we show that many human tumors have heterogeneous and often reduced...
3.
Landis C, Zhang S, Benavides G, Scott S, Li Y, Redmann M, et al.
ACS Chem Biol
. 2018 Jun;
13(8):2048-2057.
PMID: 29905460
Tumor heterogeneity has hampered the development of novel effective therapeutic options for aggressive cancers, including the deadly primary adult brain tumor glioblastoma (GBM). Intratumoral heterogeneity is partially attributed to the...
4.
Landis C, Tran A, Scott S, Griguer C, Hjelmeland A
Biochim Biophys Acta Rev Cancer
. 2018 Jan;
1869(2):175-188.
PMID: 29378228
De-regulated cellular energetics is an emerging hallmark of cancer with alterations to glycolysis, oxidative phosphorylation, the pentose phosphate pathway, lipid oxidation and synthesis and amino acid metabolism. Understanding and targeting...
5.
Boyd N, Walker K, Fried J, Hackney J, McDonald P, Benavides G, et al.
JCI Insight
. 2017 Dec;
2(24).
PMID: 29263302
Tumor microenvironments can promote stem cell maintenance, tumor growth, and therapeutic resistance, findings linked by the tumor-initiating cell hypothesis. Standard of care for glioblastoma (GBM) includes temozolomide chemotherapy, which is...