Catherine Gratas
Overview
Explore the profile of Catherine Gratas including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
277
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0
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Recent Articles
1.
Oliver L, Landais Y, Gratas C, Cartron P, Paris F, Heymann D, et al.
Stem Cell Res Ther
. 2024 Nov;
15(1):424.
PMID: 39538257
Background: The interaction between mesenchymal stem cells (MSC) and Glioblastoma (GBM), although potentially of the highest importance, is ill-understood. This is due, in part, to the lack of relevant experimental...
2.
Renoult O, Laurent-Blond M, Awada H, Oliver L, Joalland N, Croyal M, et al.
Neuro Oncol
. 2024 Jun;
26(9):1572-1586.
PMID: 38869884
Background: Glioblastoma (GBM) is a highly aggressive tumor with unmet therapeutic needs, which can be explained by extensive intra-tumoral heterogeneity and plasticity. In this study, we aimed to investigate the...
3.
Rabe M, Fonteneau L, Oliver L, Morales-Molina A, Jubelin C, Garcia-Castro J, et al.
Front Cell Dev Biol
. 2022 Jun;
10:835273.
PMID: 35693929
We have observed a drug-tolerant/persister state in a human glioblastoma (GBM) cell line after exposure to temozolomide, the standard-of-care chemotherapeutic agent for GBM. We used a multicolor lentiviral genetic barcode...
4.
Alzial G, Renoult O, Paris F, Gratas C, Clavreul A, Pecqueur C
Oncogene
. 2021 Nov;
41(5):613-621.
PMID: 34764443
Brain tumors actively reprogram their cellular metabolism to survive and proliferate, thus offering potential therapeutic opportunities. Over the past decade, extensive research has been done on mutant IDH enzymes as...
5.
Salaud C, Alvarez-Arenas A, Geraldo F, Belmonte-Beitia J, Calvo G, Gratas C, et al.
Biochem Biophys Res Commun
. 2020 Sep;
533(1):139-147.
PMID: 32943183
The tumor microenvironment (TME) controls many aspects of cancer development but little is known about its effect in Glioblastoma (GBM), the main brain tumor in adults. Tumor-activated stromal cell (TASC)...
6.
Rabe M, Dumont S, Alvarez-Arenas A, Janati H, Belmonte-Beitia J, Calvo G, et al.
Cell Death Dis
. 2020 Jan;
11(1):19.
PMID: 31907355
Drug resistance limits the therapeutic efficacy in cancers and leads to tumor recurrence through ill-defined mechanisms. Glioblastoma (GBM) are the deadliest brain tumors in adults. GBM, at diagnosis or after...
7.
Chauvin C, Joalland N, Perroteau J, Jarry U, Lafrance L, Willem C, et al.
Clin Cancer Res
. 2019 Sep;
25(23):7218-7228.
PMID: 31506386
Purpose: Cellular immunotherapies are currently being explored to eliminate highly invasive and chemoradioresistant glioblastoma (GBM) cells involved in rapid relapse. We recently showed that concomitant stereotactic injections of nonalloreactive allogeneic...
8.
Fleurence J, Bahri M, Fougeray S, Faraj S, Vermeulen S, Pinault E, et al.
Int J Cancer
. 2019 Jun;
146(2):424-438.
PMID: 31241171
Stem cell chemoresistance remains challenging the efficacy of the front-line temozolomide against glioblastoma. Novel therapies are urgently needed to fight those cells in order to control tumor relapse. Here, we...
9.
Leveque X, Hochane M, Geraldo F, Dumont S, Gratas C, Oliver L, et al.
Stem Cells
. 2019 Apr;
37(8):1083-1094.
PMID: 30977188
The general population is chronically exposed to multiple environmental contaminants such as pesticides. We have previously demonstrated that human mesenchymal stem cells (MSCs) exposed in vitro to low doses of...
10.
Sery Q, Rabe M, Oliver L, Vallette F, Gratas C
Biochem Biophys Res Commun
. 2017 Oct;
493(4):1377-1383.
PMID: 28970067
Temozolomide (TMZ) is the main chemotherapeutic agent used for treating newly diagnosed Glioblastoma Multiforme (GBM), the most frequent malignant brain tumors in adults. This alkylating agent induces DNA double strand...