Catherine D Van Raamsdonk
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Explore the profile of Catherine D Van Raamsdonk including associated specialties, affiliations and a list of published articles.
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25
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1711
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Recent Articles
1.
Longakit A, Urtatiz O, Luty A, Zhang C, Hess C, Yoo A, et al.
Cancer Res Commun
. 2025 Jan;
5(2):209-225.
PMID: 39804140
These results indicate that NF1 loss in intradermal and uveal melanomas is a potentially significant finding. They emphasize the importance of neurofibromin in cAMP signaling. They show for the first...
2.
Longakit A, Bourget H, Van Raamsdonk C
Exp Eye Res
. 2024 Dec;
251:110209.
PMID: 39694408
The Mitf transcription factor is a critical regulator of the melanocyte lineage and eye development. Mitf activity in different cell types is controlled in part by ten alternative promoters and...
3.
Hassel K, Gibson A, Seflova J, Cho E, Blair N, Van Raamsdonk C, et al.
J Mol Cell Cardiol
. 2024 Oct;
197:45-58.
PMID: 39437886
Calcium (Ca) dysregulation is a hallmark feature of cardiovascular disease. Intracellular Ca regulation is essential for proper heart function and is controlled by the sarco/endoplasmic reticulum Ca ATPase (SERCA2a). Another-regulin...
4.
MEK inhibition reduced vascular tumor growth and coagulopathy in a mouse model with hyperactive GNAQ
Schrenk S, Bischoff L, Goines J, Cai Y, Vemaraju S, Odaka Y, et al.
Nat Commun
. 2023 Apr;
14(1):1929.
PMID: 37024491
Activating non-inherited mutations in the guanine nucleotide-binding protein G(q) subunit alpha (GNAQ) gene family have been identified in childhood vascular tumors. Patients experience extensive disfigurement, chronic pain and severe complications...
5.
Pop S, Urtatiz O, Van Raamsdonk C
Bio Protoc
. 2022 Jul;
12(8):e4398.
PMID: 35800096
The epidermis is the outermost layer of the skin. It is made up of mostly keratinocytes along with a small number of melanocytes and Langerhans cells. Melanocytes produce a pigment...
6.
Urtatiz O, Haage A, Tanentzapf G, Van Raamsdonk C
Elife
. 2021 Dec;
10.
PMID: 34939927
Different melanoma subtypes exhibit specific and non-overlapping sets of oncogene and tumor suppressor mutations, despite a common cell of origin in melanocytes. For example, activation of the Gα signaling pathway...
7.
Haage A, Wagner K, Deng W, Venkatesh B, Mitchell C, Goodwin K, et al.
Development
. 2020 Jun;
147(14).
PMID: 32580934
Melanoblasts disperse throughout the skin and populate hair follicles through long-range cell migration. During migration, cells undergo cycles of coordinated attachment and detachment from the extracellular matrix (ECM). Embryonic migration...
8.
Jain F, Longakit A, Huang J, Van Raamsdonk C
Pigment Cell Melanoma Res
. 2020 May;
33(6):834-849.
PMID: 32453908
The G-protein-coupled receptor, endothelin receptor B (EDNRB), is an important regulator of melanocyte survival and proliferation. It acts by stimulating downstream heterotrimeric G proteins, such as Gα and Gα ....
9.
Urtatiz O, Cook C, Huang J, Yeh I, Van Raamsdonk C
Pigment Cell Melanoma Res
. 2019 Nov;
33(1):96-111.
PMID: 31680437
Primary leptomeningeal melanocytic neoplasms represent a spectrum of rare tumors originating from melanocytes of the leptomeninges, which are the inner two membranes that protect the central nervous system. Like other...
10.
Chohan H, Esfandiarei M, Arman D, Van Raamsdonk C, van Breemen C, Friedman J, et al.
PLoS One
. 2018 Dec;
13(12):e0208835.
PMID: 30571760
The fertility of men with neurofibromatosis 1 (NF1) is reduced. Despite this observation, gonadal function has not been examined in patients with NF1. In order to assess the role of...