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Catherine Bresner

Explore the profile of Catherine Bresner including associated specialties, affiliations and a list of published articles. Areas
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Citations 1034
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Recent Articles
1.
Harvey J, Smith A, Weymouth L, Smith R, Castanho I, Hubbard L, et al.
NPJ Parkinsons Dis . 2025 Mar; 11(1):39. PMID: 40025048
Parkinson's disease is a highly heterogeneous disorder, encompassing a complex spectrum of clinical presentation including motor, sleep, cognitive and neuropsychiatric symptoms. We aimed to investigate genome-wide DNA methylation networks in...
2.
Wu L, Real R, Martinez-Carrasco A, Chia R, Lawton M, Shoai M, et al.
Brain Commun . 2024 Jul; 6(4):fcae190. PMID: 38978726
Up to 80% of Parkinson's disease patients develop dementia, but time to dementia varies widely from motor symptom onset. Dementia with Lewy bodies presents with clinical features similar to Parkinson's...
3.
Tan M, Lawton M, Pollard M, Brown E, Real R, Carrasco A, et al.
NPJ Parkinsons Dis . 2024 Jun; 10(1):113. PMID: 38849413
There are 90 independent genome-wide significant genetic risk variants for Parkinson's disease (PD) but currently only five nominated loci for PD progression. The biology of PD progression is likely to...
4.
Wu L, Real R, Martinez A, Chia R, Lawton M, Shoai M, et al.
medRxiv . 2023 Nov; PMID: 37987016
Up to 80% of Parkinson's disease patients develop dementia, but time to dementia varies widely from motor symptom onset. Dementia with Lewy bodies presents with clinical features similar to Parkinson's...
5.
Winchester L, Barber I, Lawton M, Ash J, Liu B, Evetts S, et al.
Brain Commun . 2023 Jan; 5(1):fcac343. PMID: 36694577
Biomarkers to aid diagnosis and delineate the progression of Parkinson's disease are vital for targeting treatment in the early phases of the disease. Here, we aim to discover a multi-protein...
6.
Real R, Martinez-Carrasco A, Reynolds R, Lawton M, Tan M, Shoai M, et al.
Brain . 2022 Nov; 146(5):1873-1887. PMID: 36348503
Parkinson's disease is one of the most common age-related neurodegenerative disorders. Although predominantly a motor disorder, cognitive impairment and dementia are important features of Parkinson's disease, particularly in the later...
7.
Bellenguez C, Kucukali F, Jansen I, Kleineidam L, Moreno-Grau S, Amin N, et al.
Nat Genet . 2022 Apr; 54(4):412-436. PMID: 35379992
Characterization of the genetic landscape of Alzheimer's disease (AD) and related dementias (ADD) provides a unique opportunity for a better understanding of the associated pathophysiological processes. We performed a two-stage...
8.
Tan M, Lawton M, Jabbari E, Reynolds R, Iwaki H, Blauwendraat C, et al.
Mov Disord . 2020 Oct; 36(2):424-433. PMID: 33111402
Background: There are currently no treatments that stop or slow the progression of Parkinson's disease (PD). Case-control genome-wide association studies have identified variants associated with disease risk, but not progression....
9.
Tan M, Malek N, Lawton M, Hubbard L, Pittman A, Joseph T, et al.
Brain . 2019 Jul; 142(9):2828-2844. PMID: 31324919
Our objective was to define the prevalence and clinical features of genetic Parkinson's disease in a large UK population-based cohort, the largest multicentre prospective clinico-genetic incident study in the world....
10.
Malek N, Weil R, Bresner C, Lawton M, Grosset K, Tan M, et al.
J Neurol Neurosurg Psychiatry . 2018 Jan; 89(7):702-709. PMID: 29378790
Objectives: To examine the influence of the glucocerebrosidase () mutation carrier state on age at onset of Parkinson's disease (PD), the motor phenotype and cognitive function at baseline assessment in...