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Catarina Miranda-Lourenco

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Articles 15
Citations 124
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Recent Articles
1.
Farinha-Ferreira M, Miranda-Lourenco C, Galipeau C, Lenkei Z, Sebastiao A
Neuropharmacology . 2024 Dec; 266():110280. PMID: 39725123
There is renewed interest in psychedelics, such as psilocybin, as therapies for multiple difficult-to-treat psychiatric disorders. Even though psychedelics can induce highly pleasant or aversive experiences, depending on multiple personal...
2.
Fonseca-Gomes J, Costa-Coelho T, Ferreira-Manso M, Inteiro-Oliveira S, Vaz S, Aleman-Serrano N, et al.
Mol Ther . 2024 Dec; 33(1):421. PMID: 39672159
No abstract available.
3.
Fonseca-Gomes J, Costa-Coelho T, Ferreira-Manso M, Inteiro-Oliveira S, Vaz S, Aleman-Serrano N, et al.
Mol Ther . 2024 Aug; 32(10):3372-3401. PMID: 39205389
In Alzheimer's disease (AD), amyloid β (Aβ)-triggered cleavage of TrkB-FL impairs brain-derived neurotrophic factor (BDNF) signaling, thereby compromising neuronal survival, differentiation, and synaptic transmission and plasticity. Using cerebrospinal fluid and...
4.
Farinha-Ferreira M, Magalhaes D, Neuparth-Sottomayor M, Rafael H, Miranda-Lourenco C, Sebastiao A
J Neurochem . 2024 Mar; 168(9):2443-2460. PMID: 38430009
Reductionistic research on depressive disorders has been hampered by the limitations of animal models. Recently, it has been hypothesized that neuroinflammation is a key player in depressive disorders. The Wistar-Kyoto...
5.
Miranda-Lourenco C, Rosa J, Rei N, Belo R, Lopes A, Silva D, et al.
Int J Mol Sci . 2023 Nov; 24(22). PMID: 38003438
Rett Syndrome is an X-linked neurodevelopmental disorder (RTT; OMIM#312750) associated to mutations. MeCP2 dysfunction is seen as one cause for the deficiencies found in brain-derived neurotrophic factor (BDNF) signaling, since...
6.
Farinha-Ferreira M, Rei N, Fonseca-Gomes J, Miranda-Lourenco C, Serrao P, Vaz S, et al.
Neuropharmacology . 2022 Jun; 214:109155. PMID: 35660545
Chronic adolescent cannabinoid receptor agonist exposure has been shown to lead to persistent increases in depressive-like behaviors. This has been a key obstacle to the development of cannabinoid-based therapeutics. However,...
7.
Ferreira C, Marttinen M, Coelho J, Paldanius K, Takalo M, Makinen P, et al.
Neurobiol Dis . 2021 Dec; 163:105603. PMID: 34954322
Alzheimer's disease (AD) is the most common form of dementia, which is neuropathologically characterized by extracellular senile plaques containing amyloid-β and intracellular neurofibrillary tangles composed of hyperphosphorylated tau protein. Previous...
8.
Paulo S, Miranda-Lourenco C, Belo R, Rodrigues R, Fonseca-Gomes J, Tanqueiro S, et al.
Curr Issues Mol Biol . 2021 Dec; 43(3):2305-2319. PMID: 34940136
The increasing consumption of sugar and fat seen over the last decades and the consequent overweight and obesity, were recently linked with a deleterious effect on cognition and synaptic function....
9.
Miranda-Lourenco C, Ribeiro-Rodrigues L, Fonseca-Gomes J, Tanqueiro S, Belo R, Ferreira C, et al.
Pharmacol Res . 2020 Nov; 162:105281. PMID: 33161136
Neurotrophins are a well-known family of neurotrophic factors that play an important role both in the central and peripheral nervous systems, where they modulate neuronal survival, development, function and plasticity....
10.
Miranda-Lourenco C, Duarte S, Palminha C, Gaspar C, Rodrigues T, Magalhaes-Cardoso T, et al.
Neurobiol Dis . 2020 Aug; 145:105043. PMID: 32798727
Rett syndrome (RTT; OMIM#312750) is mainly caused by mutations in the X-linked MECP2 gene (methyl-CpG-binding protein 2 gene; OMIM*300005), which leads to impairments in the brain-derived neurotrophic factor (BDNF) signalling....