Cassandra P Smith
Overview
Explore the profile of Cassandra P Smith including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
284
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Recent Articles
1.
Cui W, Bennett A, Zhang P, Barrow K, Kearney S, Hankey K, et al.
Sci Rep
. 2016 Apr;
6:23612.
PMID: 27029502
Cachexia, or muscle wasting, is a serious health threat to victims of radiological accidents or patients receiving radiotherapy. Here, we propose a non-human primate (NHP) radiation-induced cachexia model based on...
2.
Carter C, Jones J, Barrow K, Kieta K, Taylor-Howell C, Kearney S, et al.
Health Phys
. 2015 Oct;
109(5):466-78.
PMID: 26425906
Radiation-induced lung injury is highly complex and characterized by multiple pathologies, which occur over time and sporadically throughout the lung. This complexity makes biomarker investigations and medical countermeasure screenings challenging....
3.
MacVittie T, Bennett A, Farese A, Taylor-Howell C, Smith C, Gibbs A, et al.
Health Phys
. 2015 Oct;
109(5):427-39.
PMID: 26425903
A nonhuman primate (NHP) model of acute high-dose, partial-body irradiation with 5% bone marrow (PBI/BM5) sparing was used to assess the effect of Neupogen® [granulocyte colony stimulating factor (G-CSF)] to...
4.
Zhang P, Cui W, Hankey K, Gibbs A, Smith C, Taylor-Howell C, et al.
Health Phys
. 2015 Oct;
109(5):374-90.
PMID: 26425899
Exposure to sufficiently high doses of ionizing radiation is known to cause fibrosis in many different organs and tissues. Connective tissue growth factor (CTGF/CCN2), a member of the CCN family...
5.
Hankey K, Farese A, Blaauw E, Gibbs A, Smith C, Katz B, et al.
Radiat Res
. 2015 Jun;
183(6):643-55.
PMID: 26035709
Leukocyte growth factors (LGF), such as filgrastim, pegfilgrastim and sargramostim, have been used to mitigate the hematologic symptoms of acute radiation syndrome (ARS) after radiation accidents. Although these pharmaceuticals are...
6.
Farese A, Brown C, Smith C, Gibbs A, Katz B, Johnson C, et al.
Health Phys
. 2013 Nov;
106(1):39-47.
PMID: 24276548
The identification of the optimal administration schedule for an effective medical countermeasure is critical for the effective treatment of individuals exposed to potentially lethal doses of radiation. The efficacy of...
7.
Farese A, Cohen M, Katz B, Smith C, Gibbs A, Cohen D, et al.
Radiat Res
. 2012 Dec;
179(1):89-100.
PMID: 23210705
Treatment of individuals exposed to potentially lethal doses of radiation is of paramount concern to health professionals and government agencies. We evaluated the efficacy of filgrastim to increase survival of...
8.
Farese A, Cohen M, Katz B, Smith C, Jackson 3rd W, Cohen D, et al.
Health Phys
. 2012 Aug;
103(4):367-82.
PMID: 22929469
The development of medical countermeasures against the hematopoietic subsyndrome of the acute radiation syndrome requires well characterized and validated animal models. The model must define the radiation dose- and time-dependent...