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Cassandra M Modahl

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Articles 28
Citations 290
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Recent Articles
1.
French S, Da Silva R, Storm J, Wastika C, Cullen I, Have M, et al.
Parasit Vectors . 2025 Jan; 18(1):32. PMID: 39881388
Mosquitoes are responsible for the transmission of numerous pathogens, including Plasmodium parasites, arboviruses and filarial worms. They pose a significant risk to public health with over 200 million cases of...
2.
Dawson C, Bartlett K, Wilkinson M, Ainsworth S, Albulescu L, Kazandijan T, et al.
PLoS Negl Trop Dis . 2024 Oct; 18(10):e0012570. PMID: 39423239
Background: Variation in snake venoms is well documented, both between and within species, with intraspecific venom variation often correlated with geographically distinct populations. The puff adder, Bitis arietans, is widely...
3.
Alsolaiss J, Leeming G, Da Silva R, Alomran N, Casewell N, Habib A, et al.
Toxins (Basel) . 2024 Jun; 16(6). PMID: 38922170
Snakebite envenoming is a neglected tropical disease that causes >100,000 deaths and >400,000 cases of morbidity annually. Despite the use of mouse models, severe local envenoming, defined by morbidity-causing local...
4.
Bartlett K, Hall S, Rasmussen S, Crittenden E, Dawson C, Albulescu L, et al.
Proc Natl Acad Sci U S A . 2024 Apr; 121(19):e2315597121. PMID: 38687786
Snakebite envenoming is a neglected tropical disease that causes substantial mortality and morbidity globally. The venom of African spitting cobras often causes permanent injury via tissue-destructive dermonecrosis at the bite...
5.
Smith C, Modahl C, Galindo D, Larson K, Maroney S, Bahrabadi L, et al.
Mol Cell Proteomics . 2024 Apr; 23(6):100779. PMID: 38679388
New treatments that circumvent the pitfalls of traditional antivenom therapies are critical to address the problem of snakebite globally. Numerous snake venom toxin inhibitors have shown promising cross-species neutralization of...
6.
Alonso L, van Thiel J, Slagboom J, Dunstan N, Modahl C, Jackson T, et al.
Toxins (Basel) . 2024 Apr; 16(4). PMID: 38668606
This study provides a new methodology for the rapid analysis of numerous venom samples in an automated fashion. Here, we use LC-MS (Liquid Chromatography-Mass Spectrometry) for venom separation and toxin...
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Modahl C, Han S, van Thiel J, Vaz C, Dunstan N, Frietze S, et al.
BMC Genomics . 2024 Feb; 25(1):186. PMID: 38365592
Background: Venom systems are ideal models to study genetic regulatory mechanisms that underpin evolutionary novelty. Snake venom glands are thought to share a common origin, but there are major distinctions...
9.
Thambi P, Modahl C, Kini R
Int J Mol Sci . 2024 Feb; 25(3). PMID: 38338961
is a major vector that transmits arboviruses through the saliva injected into the host. Salivary proteins help in uninterrupted blood intake and enhance the transmission of pathogens. We studied Niemann-Pick...
10.
Modahl C, Chowdhury A, Low D, Manuel M, Misse D, Kini R, et al.
Sci Rep . 2023 Jul; 13(1):11271. PMID: 37438463
Dengue (DENV) and chikungunya (CHIKV) viruses are among the most preponderant arboviruses. Although primarily transmitted through the bite of Aedes aegypti mosquitoes, Aedes albopictus and Aedes malayensis are competent vectors...