Cassandra Herbert
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Explore the profile of Cassandra Herbert including associated specialties, affiliations and a list of published articles.
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8
Citations
18
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Recent Articles
1.
Devarkar S, Budding C, Pathirage C, Kavoor A, Herbert C, Limbach P, et al.
Nucleic Acids Res
. 2025 Mar;
53(5).
PMID: 40036503
The average eukaryotic transfer ribonucleic acid (tRNA) contains 13 post-transcriptional modifications; however, their functional impact is largely unknown. Our understanding of the complex tRNA aminoacylation machinery in metazoans also remains...
2.
Hwang S, Liao H, Barondeau K, Han X, Herbert C, McConie H, et al.
Cell Rep
. 2025 Jan;
44(1):115167.
PMID: 39786998
tRNA modifications are critical for several aspects of their functions, including decoding, folding, and stability. Using a multifaceted approach encompassing eCLIP-seq and nanopore tRNA-seq, we show that the human tRNA...
3.
Devarkar S, Budding C, Pathirage C, Kavoor A, Herbert C, Limbach P, et al.
bioRxiv
. 2024 Dec;
PMID: 39677689
The average eukaryotic tRNA contains 13 posttranscriptional modifications; however, their functional impact is largely unknown. Our understanding of the complex tRNA aminoacylation machinery in metazoans also remains limited. Herein, using...
4.
Hwang S, Liao H, Barondeau K, Han X, Herbert C, McConie H, et al.
bioRxiv
. 2024 Oct;
PMID: 39416027
tRNA modifications are critical for several aspects of their functions, including decoding, folding, and stability. Using a multifaceted approach encompassing eCLIP-seq and Nanopore tRNA-seq, we show that the human tRNA...
5.
Kelley M, Holmes C, Herbert C, Rayhan A, Joves J, Uhran M, et al.
Insect Mol Biol
. 2024 Aug;
34(1):65-80.
PMID: 39105593
Mosquitoes such as Aedes aegypti must consume a blood meal for the nutrients necessary for egg production. Several transcriptome and proteome changes occur post-blood meal that likely corresponds with codon...
6.
Herbert C, Valesyan S, Kist J, Limbach P
Annu Rev Anal Chem (Palo Alto Calif)
. 2024 Apr;
17(1):47-68.
PMID: 38594935
Ribonucleic acids (RNAs) are key biomolecules responsible for the transmission of genetic information, the synthesis of proteins, and modulation of many biochemical processes. They are also often the key components...
7.
Herbert C, Ohrnberger C, Quinlisk E, Addepalli B, Limbach P
Biomedicines
. 2023 Dec;
11(12).
PMID: 38137491
The activated forms of the environmental pollutant benzo[a]pyrene (B[a]P), such as benzo[a]pyrene diol epoxide (BPDE), are known to cause damage to genomic DNA and proteins. However, the impact of BPDE...
8.
Kelley M, Holmes C, Herbert C, Rayhan A, Joves J, Uhran M, et al.
bioRxiv
. 2023 Dec;
PMID: 38076852
Mosquitoes such as must consume a blood meal for the nutrients necessary for egg production. Several transcriptome and proteome changes occur post blood meal that likely corresponds with codon usage...
9.
Kelley M, Uhran M, Herbert C, Yoshida G, Watts E, Limbach P, et al.
Insect Biochem Mol Biol
. 2022 Feb;
143:103741.
PMID: 35181477
As carriers of multiple human diseases, understanding the mechanisms behind mosquito reproduction may have implications for remediation strategies. Transfer RNA (tRNA) acts as the adapter molecule of amino acids and...
10.
Herbert C, Dzowo Y, Urban A, Kiggins C, Resendiz M
Biochemistry
. 2018 Apr;
57(20):2971-2983.
PMID: 29683663
Understanding how oxidatively damaged RNA interacts with ribonucleases is important because of its proposed role in the development and progression of disease. Thus, understanding structural aspects of RNA containing lesions...