Cassandra Bazile
Overview
Explore the profile of Cassandra Bazile including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
870
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Recent Articles
1.
Bazile C, Abdel Malik M, Ackeifi C, Anderson R, Beck R, Donath M, et al.
Front Immunol
. 2024 Oct;
15:1470677.
PMID: 39411715
Type 1 diabetes (T1D) is an autoimmune disease characterized by the destruction of insulin-producing β-cells in the pancreas. This destruction leads to chronic hyperglycemia, necessitating lifelong insulin therapy to manage...
2.
Wright J, Bazile C, Clark E, Carlesso G, Boucher J, Kleiman E, et al.
Front Immunol
. 2021 Sep;
12:705307.
PMID: 34512628
While apoptosis plays a role in B-cell self-tolerance, its significance in preventing autoimmunity remains unclear. Here, we report that dysregulated B cell apoptosis leads to delayed onset autoimmune phenotype in...
3.
Van Nostrand E, Freese P, Pratt G, Wang X, Wei X, Xiao R, et al.
Nature
. 2021 Jan;
589(7842):E5.
PMID: 33402748
No abstract available.
4.
Van Nostrand E, Freese P, Pratt G, Wang X, Wei X, Xiao R, et al.
Nature
. 2020 Jul;
583(7818):711-719.
PMID: 32728246
Many proteins regulate the expression of genes by binding to specific regions encoded in the genome. Here we introduce a new data set of RNA elements in the human genome...
5.
Dominguez D, Freese P, Alexis M, Su A, Hochman M, Palden T, et al.
Mol Cell
. 2018 Jun;
70(5):854-867.e9.
PMID: 29883606
RNA binding proteins (RBPs) orchestrate the production, processing, and function of mRNAs. Here, we present the affinity landscapes of 78 human RBPs using an unbiased assay that determines the sequence,...
6.
Taliaferro J, Lambert N, Sudmant P, Dominguez D, Merkin J, Alexis M, et al.
Mol Cell
. 2016 Oct;
64(2):294-306.
PMID: 27720642
Many RNA binding proteins (RBPs) bind specific RNA sequence motifs, but only a small fraction (∼15%-40%) of RBP motif occurrences are occupied in vivo. To determine which contextual features discriminate...