Cassandra B Jabara
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Explore the profile of Cassandra B Jabara including associated specialties, affiliations and a list of published articles.
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10
Citations
679
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Recent Articles
1.
Marks P, Garcia S, Martinez Barrio A, Belhocine K, Bernate J, Bharadwaj R, et al.
Genome Res
. 2019 Mar;
29(4):635-645.
PMID: 30894395
Large-scale population analyses coupled with advances in technology have demonstrated that the human genome is more diverse than originally thought. To date, this diversity has largely been uncovered using short-read...
2.
Barnard R, Chopra A, James I, Blinco J, Watson M, Jabara C, et al.
Antivir Ther
. 2016 May;
21(7):567-577.
PMID: 27219495
Background: Use of direct-acting antiviral drugs (DAAs) that target HCV may be hampered by the rapid selection of viral strains that harbour drug resistance-associated variants (RAVs). These RAVs are often...
3.
Jabara C, Hu F, Mollan K, Williford S, Menezes P, Yang Y, et al.
Antimicrob Agents Chemother
. 2014 Aug;
58(10):6079-92.
PMID: 25092699
HIV coinfection accelerates disease progression in chronic hepatitis C and reduces sustained antiviral responses (SVR) to interferon-based therapy. New direct-acting antivirals (DAAs) promise higher SVR rates, but the selection of...
4.
Grammatikos G, Jabara C, Ahmad M, Herrmann E, Zeuzem S, Welsch C
Antivir Ther
. 2014 Jan;
19(5):455-61.
PMID: 24457994
Background: Subtype-specific response to ketoamide NS3 protease inhibitors is observed in patients with genotype 1 HCV infection. Whether the genetic diversity in the molecular target site of ketoamide compounds prior...
5.
Ping L, Jabara C, Rodrigo A, Hudelson S, Piwowar-Manning E, Wang L, et al.
PLoS One
. 2013 Oct;
8(9):e71557.
PMID: 24086252
In the HPTN 052 study, transmission between HIV-discordant couples was reduced by 96% when the HIV-infected partner received suppressive antiretroviral therapy (ART). We examined two transmission events where the newly...
6.
Sturdevant C, Dow A, Jabara C, Joseph S, Schnell G, Takamune N, et al.
PLoS Pathog
. 2013 Jan;
8(12):e1003094.
PMID: 23300446
HIV-1 subtype B replication in the CNS can occur in CD4+ T cells or macrophages/microglia in adults. However, little is known about CNS infection in children or the ability of...
7.
Jabara C, Jones C, Roach J, Anderson J, Swanstrom R
Proc Natl Acad Sci U S A
. 2011 Dec;
108(50):20166-71.
PMID: 22135472
Viruses can create complex genetic populations within a host, and deep sequencing technologies allow extensive sampling of these populations. Limitations of these technologies, however, potentially bias this sampling, particularly when...
8.
Anderson J, Ping L, Dibben O, Jabara C, Arney L, Kincer L, et al.
PLoS Pathog
. 2010 Sep;
6(8):e1001053.
PMID: 20808902
HIV-1 is present in anatomical compartments and bodily fluids. Most transmissions occur through sexual acts, making virus in semen the proximal source in male donors. We find three distinct relationships...
9.
Harrington P, Schnell G, Letendre S, Ritola K, Robertson K, Hall C, et al.
AIDS
. 2009 May;
23(8):907-15.
PMID: 19414991
Objectives: To characterize HIV-1 env compartmentalization between cerebrospinal fluid (CSF) and peripheral blood plasma over all stages of the HIV-1 disease course, and to determine the relationship between the extent...
10.
Reeves J, Lee F, Miamidian J, Jabara C, Juntilla M, Doms R
J Virol
. 2005 Mar;
79(8):4991-9.
PMID: 15795284
Enfuvirtide (ENF/T-20/Fuzeon), the first human immunodeficiency virus (HIV) entry inhibitor to be licensed, targets a structural intermediate of the entry process. ENF binds the HR1 domain in gp41 after Env...