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Casper M Sigvardsen

Explore the profile of Casper M Sigvardsen including associated specialties, affiliations and a list of published articles. Areas
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Citations 19
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Recent Articles
1.
Miranda-Cervantes A, Fritzen A, Raun S, Hodek O, Moller L, Johann K, et al.
Nat Commun . 2025 Jan; 16(1):345. PMID: 39746949
Metabolic flexibility in skeletal muscle is essential for maintaining healthy glucose and lipid metabolism, and its dysfunction is closely linked to metabolic diseases. Exercise enhances metabolic flexibility, making it an...
2.
Sigvardsen C, Richter M, Engelbeen S, Kleinert M, Richter E
Trends Endocrinol Metab . 2024 Oct; PMID: 39472228
Growth differentiation factor 15 (GDF15) is a member of the transforming growth factor-β (TGF-β) superfamily. Despite its identification over 20 years ago, the functions of GDF15 remain complex and not...
3.
Voldstedlund C, Sjoberg K, Schlabs F, Sigvardsen C, Andersen N, Holst J, et al.
Diabetologia . 2024 Apr; 67(7):1386-1398. PMID: 38662135
Aims/hypothesis: Exercise has a profound effect on insulin sensitivity in skeletal muscle. The euglycaemic-hyperinsulinaemic clamp (EHC) is the gold standard for assessment of insulin sensitivity but it does not reflect...
4.
Sjoberg K, Sigvardsen C, Alvarado-Diaz A, Andersen N, Larance M, Seeley R, et al.
Cell Metab . 2023 Jul; 35(8):1327-1340.e5. PMID: 37473755
Growth differentiation factor 15 (GDF15) induces weight loss and increases insulin action in obese rodents. Whether and how GDF15 improves insulin action without weight loss is unknown. Obese rats were...