Casey L Egan
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Explore the profile of Casey L Egan including associated specialties, affiliations and a list of published articles.
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6
Citations
329
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Recent Articles
1.
Fuller O, McLennan E, Egan C, Perera N, Terry L, Pyun J, et al.
iScience
. 2025 Feb;
28(2):111752.
PMID: 39898049
Exercise improves cognitive function in Alzheimer's disease (AD) via mechanism that are not fully clear. Here, we first examined the effect of voluntary exercise training (VET) on energy metabolism and...
2.
Fuller O, Egan C, Robinson T, Perera N, Latchman H, Terry L, et al.
Life Metab
. 2025 Jan;
3(1):load043.
PMID: 39871877
Obesity has been linked to a range of pathologies, including dementia. In contrast, regular physical activity is associated with the prevention or reduced progression of neurodegeneration. Specifically, physical activity can...
3.
Hjorth M, Egan C, Telles G, Pal M, Gallego-Ortega D, Fuller O, et al.
J Sport Health Sci
. 2024 Sep;
14:100991.
PMID: 39341495
Purpose: Regular exercise can reduce incidence and progression of breast cancer, but the mechanisms for such effects are not fully understood. The purpose of this study was to examine the...
4.
Fuller O, McLennan E, Egan C, Burrows E, Febbraio M
Behav Brain Res
. 2023 Dec;
460:114810.
PMID: 38122903
Frontotemporal dementia (FTD) is a neurodegenerative disorder that affects the frontal and temporal lobes of the brain, primarily in individuals under 65 years of age, and is the second most...
5.
Boslem E, Reibe S, Carlessi R, Smeuninx B, Tegegne S, Egan C, et al.
Sci Adv
. 2023 Sep;
9(37):eadh0831.
PMID: 37703359
The incidence of hepatocellular carcinoma (HCC) is rapidly rising largely because of increased obesity leading to nonalcoholic steatohepatitis (NASH), a known HCC risk factor. There are no approved treatments to...
6.
Brunner J, Vogel A, Lercher A, Caldera M, Korosec A, Puhringer M, et al.
Nat Metab
. 2020 Nov;
2(12):1427-1442.
PMID: 33199895
Adipose tissue macrophages (ATMs) display tremendous heterogeneity depending on signals in their local microenvironment and contribute to the pathogenesis of obesity. The phosphoinositide 3-kinase (PI3K) signalling pathway, antagonized by the...
7.
Whitham M, Pal M, Petzold T, Hjorth M, Egan C, Brunner J, et al.
Am J Physiol Endocrinol Metab
. 2019 Aug;
317(4):E597-E604.
PMID: 31386565
It has been suggested that interleukin-6 (IL-6) produced by adipocytes in obesity leads to liver insulin resistance, although this hypothesis has never been definitively tested. Accordingly, we did so by...
8.
Whitham M, Parker B, Friedrichsen M, Hingst J, Hjorth M, Hughes W, et al.
Cell Metab
. 2018 Jan;
27(1):237-251.e4.
PMID: 29320704
Exercise stimulates the release of molecules into the circulation, supporting the concept that inter-tissue signaling proteins are important mediators of adaptations to exercise. Recognizing that many circulating proteins are packaged...